Protein: GGPPS
Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)

Gene: GGPPS, GGPS1
Organism: Homo sapiens
Interactions: 57
UniProt ID: O95749

Gene Ontology (top 5):
GO:0004161 - dimethylallyltranstransferase activity
GO:0004311 - geranylgeranyl diphosphate synthase activity
GO:0004337 - (2E,6E)-farnesyl diphosphate synthase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343665

GGPPS
Geranylgeranyl pyrophosphate synthase

4

13

High-throughput

0.893

High

343676

IQGA1
Ras GTPase-activating-like protein IQGAP1

3

0

High-throughput

0.638

High

343709

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

3

0

High-throughput

0.638

High

279257

TULP3
Tubby-related protein 3

3

0

High-throughput

0.634

High

343683

FX4L6
Forkhead box protein D4-like 6

3

1

High-throughput

0.609

High

74325

ZBT42
Zinc finger and BTB domain-containing protein 42

2

0

High-throughput

0.602

High

343690

TAD2B
Transcriptional adapter 2-beta

2

0

High-throughput

0.602

High

343691

SPA24
Spermatogenesis-associated protein 24

2

0

High-throughput

0.602

High

343707

UNKL
Putative E3 ubiquitin-protein ligase UNKL

2

0

High-throughput

0.602

High

343669

FOSL1
Fos-related antigen 1

2

1

High-throughput

0.601

High

65960

CCD69
Coiled-coil domain-containing protein 69

2

0

High-throughput

0.585

High

343708

SLTM
SAFB-like transcription modulator

2

0

High-throughput

0.585

High

140096

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

343679

FOXD4
Forkhead box protein D4

2

1

High-throughput

0.574

High

343698

ZN669
Zinc finger protein 669

2

1

High-throughput

0.574

High

128561

ATOX1
Copper transport protein ATOX1

1

0

High-throughput

0.549

High

343667

TFPT
TCF3 fusion partner

1

0

High-throughput

0.513

High

343675

S10A7
Protein S100-A7

1

0

High-throughput

0.513

High

343678

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.513

High

343692

CDR2L
Cerebellar degeneration-related protein 2-like

1

0

High-throughput

0.513

High

343697

TRI41
E3 ubiquitin-protein ligase TRIM41

1

0

High-throughput

0.513

High

343670

HXB6
Homeobox protein Hox-B6

1

1

High-throughput

0.489

High

343686

LBX2
Transcription factor LBX2

1

1

High-throughput

0.489

High

343699

ZN707
Zinc finger protein 707

1

1

High-throughput

0.489

High

343700

ZN625
Zinc finger protein 625

1

1

High-throughput

0.489

High

343671

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

343677

ATX1
Ataxin-1

1

2

High-throughput

0.479

High

343688

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

343674

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

343673

HXA5
Homeobox protein Hox-A5

1

1

High-throughput

0.437

High

261030

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

343703

NDEL1
Nuclear distribution protein nudE-like 1

1

0

High-throughput

0.426

High

66570

CC85C
Coiled-coil domain-containing protein 85C

3

0

High-throughput

0.347

High

343682

TUSC1
Tumor suppressor candidate gene 1 protein

3

0

High-throughput

0.347

High

343705

ZN696
Zinc finger protein 696

3

0

High-throughput

0.347

High

343668

ECP
Eosinophil cationic protein

3

0

High-throughput

0.345

High

343672

PACA
Pituitary adenylate cyclase-activating polypeptide

2

0

High-throughput

0.328

High

343681

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

343687

ZN517
Zinc finger protein 517

2

0

High-throughput

0.328

High

343689

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

343704

IKZF5
Zinc finger protein Pegasus

2

0

High-throughput

0.328

High

343711

T3JAM
TRAF3-interacting JNK-activating modulator

2

0

High-throughput

0.328

High

343666

IGF2
Insulin-like growth factor 2

2

0

High-throughput

0.313

High

343680

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low

343684

AVPI1
Arginine vasopressin-induced protein 1

1

0

High-throughput

0.279

Low

343685

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

0

High-throughput

0.279

Low

343693

CMA1C
Protein CIMAP1C

1

0

High-throughput

0.279

Low

343694

CF107
Cilia- and flagella-associated protein 107

1

0

High-throughput

0.279

Low

343696

MB3L2
Methyl-CpG-binding domain protein 3-like 2

1

0

High-throughput

0.279

Low

343701

F218A
Protein FAM218A

1

0

High-throughput

0.279

Low

343712

CCL26
C-C motif chemokine 26

1

0

High-throughput

0.279

Low

343702

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

336179

TNF6B
Tumor necrosis factor receptor superfamily member 6B

1

0

High-throughput

0.232

Low

343695

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low

343706

Q9H8E5
cDNA FLJ13705 fis, clone PLACE2000302

1

0

High-throughput

0.232

Low

343710

EGFL7
Epidermal growth factor-like protein 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025