Interactor 1: DRD2 (P14416)
D(2) dopamine receptor (Dopamine D2 receptor)
Gene: DRD2
Interactor 2: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 1.00 | 0.754 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~Arrestin_C, 7tm_1~Arrestin_N |
| Common GO terms | GO:0002031 - G protein-coupled receptor internalization GO:0002092 - positive regulation of receptor internalization GO:0005886 - plasma membrane GO:0007628 - adult walking behavior GO:0030139 - endocytic vesicle and 4 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
