Protein: 5HT2A
5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)

Gene: 5HT2A, HTR2A
Organism: Homo sapiens
Interactions: 27
UniProt ID: P28223

Gene Ontology (top 5):
GO:0001587 - Gq/11-coupled serotonin receptor activity
GO:0001618 - virus receptor activity
GO:0001659 - temperature homeostasis
GO:0002720 - positive regulation of cytokine production involved in immune response
GO:0004993 - G protein-coupled serotonin receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

701444

5HT2C
5-hydroxytryptamine receptor 2C

2

16

Small-scale

0.743

High

638879

CNR1
Cannabinoid receptor 1

1

18

Small-scale

0.665

High

701449

ARF6
ADP-ribosylation factor 6

2

3

Small-scale

0.629

High

701452

ARF1
ADP-ribosylation factor 1

2

3

Small-scale

0.624

High

701443

5HT2A
5-hydroxytryptamine receptor 2A

1

16

Small-scale

0.618

High

701445

ARRB2
Beta-arrestin-2

1

6

Small-scale

0.618

High

701446

5HT2B
5-hydroxytryptamine receptor 2B

1

15

Small-scale

0.618

High

701447

KS6A3
Ribosomal protein S6 kinase alpha-3

1

2

Small-scale

0.590

High

701456

GRM2
Metabotropic glutamate receptor 2

1

5

Small-scale

0.589

High

701453

DLG1
Disks large homolog 1

1

13

Small-scale

0.561

High

299738

MPDZ
Multiple PDZ domain protein

1

20

Small-scale

0.501

High

253302

JAK2
Tyrosine-protein kinase JAK2

1

10

Small-scale

0.479

High

463352

LYN
Tyrosine-protein kinase Lyn

1

7

Small-scale

0.479

High

651164

CBL
E3 ubiquitin-protein ligase CBL

1

1

Small-scale

0.479

High

701450

DLG4
Disks large homolog 4

1

15

Small-scale

0.479

High

701448

PPP5
Serine/threonine-protein phosphatase 5

1

1

Small-scale

0.457

High

701451

MAP1A
Microtubule-associated protein 1A

1

4

Small-scale

0.457

High

701457

PON2
Serum paraoxonase/arylesterase 2

1

1

Small-scale

0.457

High

701458

NTRK3
NT-3 growth factor receptor

1

2

Small-scale

0.457

High

701459

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

1

Small-scale

0.457

High

578637

GLNA
Glutamine synthetase

1

0

Small-scale

0.438

High

701460

WRIP1
ATPase WRNIP1

1

1

Small-scale

0.437

High

131334

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

4

Small-scale

0.417

High

701455

NDK3
Nucleoside diphosphate kinase 3

1

1

Small-scale

0.417

High

353921

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

Small-scale

0.238

Low

701454

RM28
Large ribosomal subunit protein bL28m

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025