HitPredict

Interactor 1: ENPL (P14625)
Endoplasmin (EC 3.6.4.-) (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25796446, 31501420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 803 Hs			1 504
+	Hs
		573377 ENPL_HUMAN (1-803): 0: 1065: 100.00		NEDD4_HUMAN (40-504): 3.86e-95: 315: 19.26
+	Hs
		573677 ENPL_HUMAN (1-803): 0: 1065: 100.00		SMUF2_HUMAN (99-504): 3.15e-96: 309: 18.95
+	Hs
		131678 HS90B_HUMAN (75-783): 0: 990: 46.26		WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54
+	Hs
		131674 HS90A_HUMAN (60-783): 0: 983: 45.07		WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54
+	Hs
		468164 HS90B_HUMAN (75-783): 0: 990: 46.26		YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00
+	Hs
		461257 HS90A_HUMAN (60-783): 0: 983: 45.07		YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00
+	Hs
		468788 HS90B_HUMAN (75-783): 0: 990: 46.26		WWP1_HUMAN (4-504): 4.94e-105: 336: 14.63
+	Hs
		461920 HS90A_HUMAN (60-783): 0: 983: 45.07		WWP1_HUMAN (4-504): 4.94e-105: 336: 14.63
+	Hs
		573550 ENPL_HUMAN (1-803): 0: 1065: 100.00		HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09
+	Hs
		468543 HS90B_HUMAN (75-783): 0: 990: 46.26		HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09
+	Hs
		461648 HS90A_HUMAN (60-783): 0: 983: 45.07		HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09
+	Sc
		579438 HSC82_YEAST (72-783): 0: 864: 47.29		RSP5_YEAST (3-504): 1.28e-97: 314: 15.25
+	Sc
		392773 HSP82_YEAST (72-783): 0: 862: 46.89		RSP5_YEAST (3-504): 1.28e-97: 314: 15.25
+	Hs
		468477 HS90B_HUMAN (75-783): 0: 990: 46.26		MAGI3_HUMAN (69-270): 8.85e-39: 153: 21.64
+	Sc
		579111 HSC82_YEAST (72-783): 0: 864: 47.29		PRP40_YEAST (177-503): 2.01e-52: 188: 12.87
+	Sc
		392479 HSP82_YEAST (72-783): 0: 862: 46.89		PRP40_YEAST (177-503): 2.01e-52: 188: 12.87
+	Sc
		579963 HSC82_YEAST (72-783): 0: 864: 47.29		TOM1_YEAST (260-504): 8.95e-40: 156: 12.10
+	Sc
		393234 HSP82_YEAST (72-783): 0: 862: 46.89		TOM1_YEAST (260-504): 8.95e-40: 156: 12.10