HitPredict

Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 227
+	Hs
		573833 PTN1_HUMAN (1-435): 0: 539: 100.00		RND1_HUMAN (6-227): 1.9e-83: 249: 53.15
+	Hs
		573648 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		436151 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		573655 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		573653 PTN1_HUMAN (1-435): 0: 539: 100.00		RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08
+	Hs
		573643 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86
+	Hs
		545198 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		573659 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOG_HUMAN (7-193): 2.82e-75: 227: 41.71
+	Hs
		120299 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48
+	Hs
		573919 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOF_HUMAN (9-191): 9.16e-51: 165: 43.01
+	Hs
		570514 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		436150 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		545197 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		570523 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RHOG_HUMAN (7-193): 2.82e-75: 227: 41.71
+	Hs
		900420 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		436276 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		914038 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08
+	Hs
		892338 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86
+	Hs
		545345 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		120410 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48