HitPredict

Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	25640309
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 727
+	Hs
		573644 PTN1_HUMAN (1-435): 0: 539: 100.00		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		545198 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC2_HUMAN (12-219): 9.54e-73: 236: 36.97
+	Hs
		573643 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC3_HUMAN (12-208): 3.69e-72: 234: 39.50
+	Hs
		573655 PTN1_HUMAN (1-435): 0: 539: 100.00		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		573659 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		573648 PTN1_HUMAN (1-435): 0: 539: 100.00		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29
+	Hs
		573653 PTN1_HUMAN (1-435): 0: 539: 100.00		RB11A_HUMAN (5-252): 2.31e-70: 230: 16.34
+	Hs
		545197 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RAC2_HUMAN (12-219): 9.54e-73: 236: 36.97
+	Hs
		570523 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		570514 PTN2_HUMAN (3-435): 3.97e-156: 449: 52.98		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29
+	Hs
		893944 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		564498 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RHOQ_HUMAN (10-225): 1.24e-84: 267: 36.53
+	Hs
		545345 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RAC2_HUMAN (12-219): 9.54e-73: 236: 36.97
+	Hs
		892338 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RAC3_HUMAN (12-208): 3.69e-72: 234: 39.50
+	Hs
		564508 PTPRS_HUMAN (1-278): 3.66e-109: 355: 30.74		RHOQ_HUMAN (10-225): 1.24e-84: 267: 36.53
+	Hs
		925235 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		950951 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		900420 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29
+	Hs
		914038 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RB11A_HUMAN (5-252): 2.31e-70: 230: 16.34
+	Hs
		900404 PTN12_HUMAN (24-314): 1e-122: 376: 33.55		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29