HitPredict

Interactor 1: EGR1 (P18146)
Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)
Gene: EGR1

Interactor 2: NAB1 (Q13506)
NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54)
Gene: NAB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.698

Property	Details
Experiments	28514442, 33961781, 7624335, 19374776
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 487
+	Hs
		505216 EGR2_HUMAN (80-425): 2.09e-91: 290: 40.70		NAB1_HUMAN (1-487): 0: 839: 100.00
+	Mm
		436782 EGR2_MOUSE (80-425): 2.78e-96: 302: 42.53		NAB1_MOUSE (1-487): 0: 805: 92.42
+	Hs
		575452 EGR1_HUMAN (1-543): 1.51e-146: 434: 100.00		NAB2_HUMAN (2-346): 6.22e-153: 447: 49.73
+	Mm
		434888 EGR1_MOUSE (1-543): 6.4e-140: 416: 87.50		NAB2_MOUSE (2-337): 8.44e-152: 444: 50.28
+	Mm
		436783 EGR2_MOUSE (80-425): 2.78e-96: 302: 42.53		NAB2_MOUSE (2-337): 8.44e-152: 444: 50.28
+	Hs
		505220 EGR2_HUMAN (80-425): 2.09e-91: 290: 40.70		NAB2_HUMAN (2-346): 6.22e-153: 447: 49.73