Interactor 1: SYDC (P14868)
Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (Cell proliferation-inducing gene 40 protein)
Gene: DARS1
Interactor 2: AIMP2 (Q13155)
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1)
Gene: AIMP2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.971 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 31792442, 35546148, 21900206, 25416956, 16189514, 31839598, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AIMP2_LysRS_bd~tRNA-synt_2, Thioredoxin_16~tRNA-synt_2 |
| Common GO terms | GO:0005829 - cytosol GO:0006412 - translation GO:0016020 - membrane GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex GO:0065003 - protein-containing complex assembly |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Cg |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
