HitPredict

Interactor 1: SON (P18583)
Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3)
Gene: SON

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0006397 - mRNA processing GO:0008380 - RNA splicing GO:0016607 - nuclear speck
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2426 Hs			1 238
+	Hs
		577606 SON_HUMAN (1-2426): 0: 655: 100.00		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		577623 SON_HUMAN (1-2426): 0: 655: 100.00		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		577690 SON_HUMAN (1-2426): 0: 655: 100.00		RBM4B_HUMAN (12-89): 4.32e-17: 81: 32.05
+	Hs
		1037810 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00
+	Hs
		952095 SCAFB_HUMAN (1309-2042): 9.77e-17: 89.6: 16.07		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		1037852 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97
+	Hs
		853883 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		992900 SCAFB_HUMAN (1309-2042): 9.77e-17: 89.6: 16.07		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		432691 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		951949 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		992756 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		1031405 TITIN_HUMAN (735-1660): 9.25e-11: 70.2: 9.62		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		1037875 PRP4K_HUMAN (1837-2057): 3.72e-14: 80.7: 21.53		RBM4B_HUMAN (12-89): 4.32e-17: 81: 32.05
+	Hs
		516609 TITIN_HUMAN (735-1660): 9.25e-11: 70.2: 9.62		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		820908 PRC2A_HUMAN (16-1077): 2.57e-09: 65.3: 9.26		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		516406 PRC2A_HUMAN (16-1077): 2.57e-09: 65.3: 9.26		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		820889 PRC2A_HUMAN (16-1077): 2.57e-09: 65.3: 9.26		TIAR_HUMAN (5-97): 6.64e-16: 77.8: 25.51