HitPredict

Interactor 1: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Interactor 2: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031492 - nucleosomal DNA binding GO:0046982 - protein heterodimerization activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 421 Hs			1 130
+	Hs
		391538 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		578445 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Hs
		555286 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Sc
		392291 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Sc
		392051 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		H2A1_YEAST (16-127): 2.97e-53: 165: 81.25