Protein: BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)

Gene: BDH, BDH1
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q02338

Gene Ontology (top 5):
GO:0003858 - 3-hydroxybutyrate dehydrogenase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0008202 - steroid metabolic process
GO:0043231 - intracellular membrane-bounded organelle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

562005

LAMP2
Lysosome-associated membrane glycoprotein 2

2

4

High-throughput

0.628

High

1036389

S39A9
Zinc transporter ZIP9

2

1

High-throughput

0.628

High

1036393

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

3

3

High-throughput

0.609

High

400681

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

5

High-throughput

0.584

High

771112

APJ
Apelin receptor

2

3

High-throughput

0.574

High

854526

S15A1
Solute carrier family 15 member 1

2

1

High-throughput

0.574

High

1036371

I13R2
Interleukin-13 receptor subunit alpha-2

2

1

High-throughput

0.574

High

1036379

GLMP
Glycosylated lysosomal membrane protein

2

1

High-throughput

0.574

High

348468

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.536

High

1036378

HUMMR
Protein MGARP

1

1

High-throughput

0.536

High

1036383

LPAR4
Lysophosphatidic acid receptor 4

1

7

High-throughput

0.536

High

1036385

S22A4
Solute carrier family 22 member 4

1

4

High-throughput

0.536

High

395944

ESR1
Estrogen receptor

2

7

High-throughput

0.521

High

622442

ELK1
ETS domain-containing protein Elk-1

2

1

High-throughput

0.521

High

1036384

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

421953

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

133241

P2Y10
Putative P2Y purinoceptor 10

1

7

High-throughput

0.489

High

732972

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

3

High-throughput

0.489

High

754016

CD80
T-lymphocyte activation antigen CD80

1

2

High-throughput

0.489

High

848476

MAGA8
Melanoma-associated antigen 8

1

2

High-throughput

0.489

High

926761

VMAT1
Chromaffin granule amine transporter

1

4

High-throughput

0.489

High

1034720

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

1

High-throughput

0.489

High

1036377

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

2

High-throughput

0.489

High

1036380

AQP3
Aquaporin-3

1

2

High-throughput

0.489

High

1036382

HDA11
Histone deacetylase 11

1

3

High-throughput

0.489

High

1036390

HCST
Hematopoietic cell signal transducer

1

1

High-throughput

0.489

High

1036391

HDAC6
Protein deacetylase HDAC6

1

2

High-throughput

0.489

High

1036395

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

1036396

NPTN
Neuroplastin

1

5

High-throughput

0.489

High

275006

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

851056

LPAR6
Lysophosphatidic acid receptor 6

1

6

High-throughput

0.479

High

1036373

MARC1
Mitochondrial amidoxime-reducing component 1

1

1

High-throughput

0.479

High

1036381

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

1036392

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

749606

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

0

High-throughput

0.458

High

1036387

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

0

High-throughput

0.458

High

128987

MEN1
Menin

1

1

High-throughput

0.437

High

848124

MAGA1
Melanoma-associated antigen 1

1

2

High-throughput

0.437

High

878982

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

940923

HDAC4
Histone deacetylase 4

1

2

High-throughput

0.437

High

1036370

CUL4A
Cullin-4A

1

1

High-throughput

0.437

High

1036375

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1036386

TMPS5
Transmembrane protease serine 5

1

4

High-throughput

0.437

High

1036374

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.407

High

378062

TNFA
Tumor necrosis factor

2

0

High-throughput

0.318

High

1036388

SACA1
Sperm acrosome membrane-associated protein 1

2

0

High-throughput

0.318

High

337169

APOM
Apolipoprotein M

1

0

High-throughput

0.279

Low

549762

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.279

Low

1036376

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

0

High-throughput

0.279

Low

1036394

B3GT5
Beta-1,3-galactosyltransferase 5

1

0

High-throughput

0.279

Low

335611

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.249

Low

872222

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

888450

TSP3
Thrombospondin-3

1

0

High-throughput

0.249

Low

907387

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.249

Low

1036372

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025