HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: EF1G2 (P36008)
Elongation factor 1-gamma 2 (EF-1-gamma 2) (Eukaryotic elongation factor 1Bgamma 2) (eEF1Bgamma 2) (Translation elongation factor 1B gamma 2)
Gene: TEF4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	19536198, 16554755, 31399574, 37295430
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 412
+	Hs
		468094 HS90B_HUMAN (5-705): 0: 1016: 61.15		EF1G_HUMAN (1-412): 7.3e-151: 435: 29.62
+	Sc
		578990 HSC82_YEAST (1-705): 0: 971: 100.00		EF1G1_YEAST (1-412): 5.89e-145: 420: 62.17
+	Sc
		392368 HSP82_YEAST (1-705): 0: 963: 95.63		EF1G1_YEAST (1-412): 5.89e-145: 420: 62.17
+	Sc
		392541 HSP82_YEAST (1-705): 0: 963: 95.63		EF1G2_YEAST (1-412): 1.25e-142: 414: 100.00
+	Sc
		392906 HSP82_YEAST (1-705): 0: 963: 95.63		YG4D_YEAST (1-215): 1.31e-49: 169: 31.25
+	Hs
		461170 HS90A_HUMAN (4-705): 0: 1007: 60.67		SYVC_HUMAN (5-239): 3.15e-29: 122: 23.14
+	Dm
		57611 Q9VAY2_DROME (3-676): 0: 826: 47.09		A1ZB71_DROME (1-204): 1.09e-53: 179: 17.54
+	Dm
		1468714 Q9VAY2_DROME (3-676): 0: 826: 47.09		Q9XYZ9_DROME (1-216): 4.49e-45: 157: 14.80