Protein: EF1G2
Elongation factor 1-gamma 2 (EF-1-gamma 2) (Eukaryotic elongation factor 1Bgamma 2) (eEF1Bgamma 2) (Translation elongation factor 1B gamma 2)

Gene: EF1G2, TEF4
Organism: Saccharomyces cerevisiae S288C
Interactions: 149
UniProt ID: P36008

Gene Ontology (top 5):
GO:0003746 - translation elongation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

737367

EF1B
Elongation factor 1-beta

4

17

Small-scale

0.905

High

713610

EF1G1
Elongation factor 1-gamma 1

2

15

High-throughput

0.776

High

579182

HSC82
ATP-dependent molecular chaperone HSC82

4

8

High-throughput

0.691

High

394439

EF1A
Elongation factor 1-alpha

3

6

High-throughput

0.662

High

779044

OLA1
Obg-like ATPase 1

3

2

High-throughput

0.662

High

779074

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

4

High-throughput

0.640

High

526380

HSP72
Heat shock protein SSA2

3

9

High-throughput

0.624

High

544431

SSB1
Ribosome-associated molecular chaperone SSB1

3

9

High-throughput

0.624

High

655619

TAF2
Transcription initiation factor TFIID subunit 2

2

1

High-throughput

0.621

High

779114

NEW1
[NU+] prion formation protein 1

2

1

High-throughput

0.621

High

779043

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

2

7

High-throughput

0.618

High

779072

BUD27
Bud site selection protein 27

2

0

Small-scale

0.610

High

779069

COPB2
Coatomer subunit beta'

3

2

High-throughput

0.609

High

670565

SIS1
Protein SIS1

2

4

High-throughput

0.601

High

775961

TCTP
Translationally-controlled tumor protein homolog

2

3

High-throughput

0.601

High

368156

THDH
Threonine dehydratase, mitochondrial

2

0

High-throughput

0.595

High

779061

IMB4
Importin subunit beta-4

2

2

High-throughput

0.588

High

779066

MGA2
Protein MGA2

2

1

High-throughput

0.588

High

392541

HSP82
ATP-dependent molecular chaperone HSP82

2

8

Small-scale

0.584

High

779091

2ABA
Protein phosphatase PP2A regulatory subunit B

2

0

High-throughput

0.576

High

438666

SC160
Protein SCP160

2

1

High-throughput

0.571

High

779075

SYEC
Glutamate--tRNA ligase, cytoplasmic

2

0

High-throughput

0.563

High

523580

HSP71
Heat shock protein SSA1

2

8

High-throughput

0.552

High

560679

KIN2
Serine/threonine-protein kinase KIN2

1

2

High-throughput

0.536

High

575580

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

3

High-throughput

0.536

High

598845

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.536

High

734068

EF2
Elongation factor 2

1

4

High-throughput

0.536

High

737826

HOG1
Mitogen-activated protein kinase HOG1

1

6

High-throughput

0.536

High

740138

RPN2
26S proteasome regulatory subunit RPN2

1

2

High-throughput

0.536

High

762943

SPT7
SAGA complex subunit SPT7

1

3

High-throughput

0.536

High

779056

MET30
F-box protein MET30

1

4

High-throughput

0.536

High

779063

RAD26
DNA repair and recombination protein RAD26

1

3

High-throughput

0.536

High

779070

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.536

High

779093

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

5

High-throughput

0.536

High

779098

GCN5
Histone acetyltransferase GCN5

1

4

High-throughput

0.536

High

779117

RAD59
DNA repair protein RAD59

1

1

High-throughput

0.536

High

779045

SLT11
Pre-mRNA-splicing factor SLT11

1

1

High-throughput

0.515

High

779073

IES1
Ino eighty subunit 1

1

1

High-throughput

0.515

High

444846

SIR3
Regulatory protein SIR3

1

0

High-throughput

0.513

High

600677

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.513

High

676627

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.513

High

779096

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.513

High

779109

BUD20
Bud site selection protein 20

1

0

High-throughput

0.513

High

599345

FUS3
Mitogen-activated protein kinase FUS3

1

6

High-throughput

0.501

High

624996

PRP6
Pre-mRNA-splicing factor 6

1

3

High-throughput

0.500

High

675286

DMC1
Meiotic recombination protein DMC1

1

1

High-throughput

0.500

High

779051

LAM1
Membrane-anchored lipid-binding protein LAM1

1

0

High-throughput

0.493

High

779090

FAP1
FKBP12-associated protein 1

1

0

High-throughput

0.493

High

779055

TEM1
Protein TEM1

1

1

High-throughput

0.489

High

779118

SMT3
Ubiquitin-like protein SMT3

1

6

High-throughput

0.481

High

364468

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.479

High

394042

EFTU
Elongation factor Tu, mitochondrial

1

7

High-throughput

0.479

High

416108

SYTC
Threonine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.479

High

416220

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

7

High-throughput

0.479

High

436375

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

6

High-throughput

0.479

High

438415

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.479

High

581847

SYKC
Lysine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.479

High

645150

PSB4
Proteasome subunit beta type-4

1

5

High-throughput

0.479

High

645716

HSP74
Heat shock protein SSA4

1

8

High-throughput

0.479

High

649600

KCC2
Calcium/calmodulin-dependent protein kinase II

1

3

High-throughput

0.479

High

661494

PSA2
Proteasome subunit alpha type-2

1

4

High-throughput

0.479

High

671615

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.479

High

675898

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.479

High

679558

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

687578

SYLC
Leucine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.479

High

706755

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

709690

BMH1
Protein BMH1

1

7

Small-scale

0.479

High

726925

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

750623

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

760233

BMH2
Protein BMH2

1

7

Small-scale

0.479

High

779042

SYG
Glycine--tRNA ligase 1, mitochondrial

1

4

High-throughput

0.479

High

779047

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.479

High

779048

YHI0
Putative proline--tRNA ligase YHR020W

1

4

High-throughput

0.479

High

779049

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

779052

RPN10
26S proteasome regulatory subunit RPN10

1

2

High-throughput

0.479

High

779053

IF1A
Eukaryotic translation initiation factor 1A

1

1

High-throughput

0.479

High

779058

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.479

High

779083

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

779089

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

779092

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.479

High

779095

PRS8
26S proteasome regulatory subunit 8 homolog

1

2

High-throughput

0.479

High

779097

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.479

High

779100

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

779105

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

779108

BRE1
E3 ubiquitin-protein ligase BRE1

1

6

Small-scale

0.479

High

779116

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.479

High

779120

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

434993

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

514567

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

647079

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

724315

PUS3
tRNA pseudouridine(38/39) synthase

1

0

High-throughput

0.458

High

779039

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.458

High

779046

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

779065

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

779068

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.458

High

779071

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

779076

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

779077

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

779081

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.458

High

779084

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

779085

DCP2
m7GpppN-mRNA hydrolase

1

0

Small-scale

0.458

High

779094

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

779106

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

779107

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

779111

SGO1
Shugoshin

1

0

High-throughput

0.458

High

779115

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

736084

ARP2
Actin-related protein 2

1

2

High-throughput

0.457

High

779101

UTP5
U3 small nucleolar RNA-associated protein 5

1

3

High-throughput

0.457

High

403449

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.445

High

427220

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

453538

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

592167

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.445

High

739336

ZUO1
Zuotin

1

3

High-throughput

0.445

High

741329

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

752109

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

779050

SSZ1
Ribosome-associated complex subunit SSZ1

1

6

High-throughput

0.445

High

779057

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.445

High

779062

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

779079

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

3

High-throughput

0.445

High

441835

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

502970

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

682237

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

779060

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

779082

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

779112

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

779113

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

779119

DBP10
ATP-dependent RNA helicase DBP10

1

5

High-throughput

0.437

High

779040

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.426

High

779054

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.426

High

779059

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

779080

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.426

High

779086

MPA43
Protein MPA43

1

0

High-throughput

0.426

High

779087

HCH1
Hsp90 co-chaperone HCH1

1

0

High-throughput

0.426

High

779104

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.426

High

779064

JEM1
DnaJ-like chaperone JEM1

1

2

High-throughput

0.407

High

575430

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

2

0

High-throughput

0.307

High

753231

MFT1
THO complex subunit MFT1

1

0

High-throughput

0.279

Low

779041

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

779103

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

779088

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.269

Low

555305

EI2BD
Translation initiation factor eIF2B subunit delta

1

0

High-throughput

0.261

Low

454984

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

689375

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

779067

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

779078

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

779099

YMC0
Uncharacterized protein YML020W

1

0

High-throughput

0.249

Low

779110

LCL2
Long chronological lifespan protein 2

1

0

High-throughput

0.249

Low

554417

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

0

High-throughput

0.232

Low

779102

PDR15
ATP-dependent permease PDR15

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025