Interactor 1: IL10 (P18893)
Interleukin-10 (IL-10) (Cytokine synthesis inhibitory factor) (CSIF)
Gene: IL10

Interactor 2: I10R1 (Q61727)
Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha) (IL-10R subunit alpha) (IL-10RA) (CDw210a) (Interleukin-10 receptor subunit 1) (IL-10R subunit 1) (IL-10R1) (CD antigen CD210)
Gene: Il10ra

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 8248239
Identification Methods protein cross-linking with a bifunctional reagent
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL10~Tissue_fac
Common GO terms GO:0010507 - negative regulation of autophagy
GO:0046427 - positive regulation of receptor signaling pathway via JAK-STAT
GO:0050728 - negative regulation of inflammatory response
GO:0050807 - regulation of synapse organization
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 178
Mm

1 575
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024