HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: ADA2 (Q02336)
SAGA complex subunit ADA2 (Transcriptional adapter 2)
Gene: ADA2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21734642
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 434
+	Hs
		283422 HS90B_HUMAN (5-705): 0: 1016: 61.15		TAD2A_HUMAN (2-434): 2.06e-146: 425: 28.86
+	Hs
		283419 HS90A_HUMAN (4-705): 0: 1007: 60.67		TAD2A_HUMAN (2-434): 2.06e-146: 425: 28.86
+	Sc
		579608 HSC82_YEAST (1-705): 0: 971: 100.00		RSC8_YEAST (5-227): 1.34e-44: 165: 16.45
+	Sc
		392929 HSP82_YEAST (1-705): 0: 963: 95.63		RSC8_YEAST (5-227): 1.34e-44: 165: 16.45
+	Hs
		468620 HS90B_HUMAN (5-705): 0: 1016: 61.15		SMRC2_HUMAN (82-354): 2.22e-12: 71.5: 10.43
+	Sc
		392439 HSP82_YEAST (1-705): 0: 963: 95.63		SWI3_YEAST (61-198): 1.75e-20: 96.1: 14.49
+	Hs
		573582 ENPL_HUMAN (3-680): 0: 887: 47.10		SMRC2_HUMAN (82-354): 2.22e-12: 71.5: 10.43
+	Hs
		573606 ENPL_HUMAN (3-680): 0: 887: 47.10		SMRC1_HUMAN (61-164): 2.02e-12: 71.5: 17.31