HitPredict

Interactor 1: K1C15 (P19012)
Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)
Gene: KRT15

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	25416956, 32296183, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 456 Hs			1 1084
+	Hs
		445063 K1C16_HUMAN (101-418): 1.73e-155: 451: 76.10		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		359364 K1C14_HUMAN (103-454): 9.83e-146: 425: 69.58		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		444383 K1C19_HUMAN (59-414): 3.71e-140: 409: 64.89		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		1071191 K1H1_HUMAN (99-417): 4.47e-126: 374: 57.81		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		280598 KRT34_HUMAN (99-417): 5.45e-120: 357: 56.56		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		445084 K1C16_HUMAN (101-418): 1.73e-155: 451: 76.10		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		57665 K1C16_HUMAN (101-418): 1.73e-155: 451: 76.10		A2BDD9_HUMAN (412-1084): 1.21e-39: 159: 99.70
+	Hs
		57666 K1C15_HUMAN (1-456): 4.76e-155: 449: 100.00		A2BDD9_HUMAN (412-1084): 1.21e-39: 159: 99.70
+	Hs
		57663 K1C14_HUMAN (103-454): 9.83e-146: 425: 69.58		A2BDD9_HUMAN (412-1084): 1.21e-39: 159: 99.70
+	Hs
		444418 K1C19_HUMAN (59-414): 3.71e-140: 409: 64.89		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		580125 K1C15_HUMAN (1-456): 4.76e-155: 449: 100.00		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		57664 K1C19_HUMAN (59-414): 3.71e-140: 409: 64.89		A2BDD9_HUMAN (412-1084): 1.21e-39: 159: 99.70
+	Hs
		444513 K1C19_HUMAN (59-414): 3.71e-140: 409: 64.89		CE164_HUMAN (20-1032): 2.66e-35: 148: 11.99
+	Hs
		57680 K1H1_HUMAN (99-417): 4.47e-126: 374: 57.81		A2BDD9_HUMAN (412-1084): 1.21e-39: 159: 99.70
+	Hs
		444517 K1C19_HUMAN (59-414): 3.71e-140: 409: 64.89		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		57660 KRT34_HUMAN (99-417): 5.45e-120: 357: 56.56		A2BDD9_HUMAN (412-1084): 1.21e-39: 159: 99.70
+	Hs
		444487 K1C19_HUMAN (59-414): 3.71e-140: 409: 64.89		MYO5C_HUMAN (338-916): 1.21e-17: 91.1: 10.24
+	Hs
		1071452 K1H1_HUMAN (99-417): 4.47e-126: 374: 57.81		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		724787 K1C17_HUMAN (98-454): 6.71e-140: 409: 68.91		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		725143 K1C17_HUMAN (98-454): 6.71e-140: 409: 68.91		MYH10_HUMAN (479-879): 3.84e-12: 73: 12.04