Protein: HFD1
Fatty aldehyde dehydrogenase HFD1 (EC 1.2.1.3) (EC 1.2.1.64) (Hexadecenal dehydrogenase)

Gene: HFD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 45
UniProt ID: Q04458

Gene Ontology (top 5):
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580033

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.584

High

527629

HSP72
Heat shock protein SSA2

2

19

High-throughput

0.552

High

670335

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.515

High

509711

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

8

High-throughput

0.501

High

822281

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

4

High-throughput

0.501

High

1046692

GIN4
Serine/threonine-protein kinase GIN4

1

2

High-throughput

0.501

High

1046691

ENV9
Probable oxidoreductase ENV9

1

4

High-throughput

0.481

High

393304

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.479

High

399882

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

2

High-throughput

0.479

High

510799

HSP77
Import motor subunit, mitochondrial

1

16

High-throughput

0.479

High

680047

CDC48
Cell division control protein 48

1

8

High-throughput

0.479

High

709970

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

739462

ZUO1
Zuotin

1

5

Small-scale

0.479

High

746940

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

2

High-throughput

0.479

High

781459

MIC60
MICOS complex subunit MIC60

1

2

High-throughput

0.479

High

785973

LONM
Lon protease homolog, mitochondrial

1

10

High-throughput

0.479

High

800917

NCB5R
NADH-cytochrome b5 reductase 1

1

2

High-throughput

0.479

High

818646

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

1

High-throughput

0.479

High

822338

ELO3
Fatty acid elongase 3

1

5

High-throughput

0.479

High

864823

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

881437

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

922651

HST2
NAD-dependent protein deacetylase HST2

1

8

High-throughput

0.479

High

782036

PET10
Protein PET10

1

0

High-throughput

0.460

High

821064

LDO16
Lipid droplet organization protein LDO16

1

0

High-throughput

0.460

High

748537

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

826276

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.458

High

1044142

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

1046689

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.458

High

1046690

BSC2
Bypass of stop codon protein 2

1

0

Small-scale

0.458

High

828535

HACD
Very-long-chain

1

1

High-throughput

0.457

High

394890

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

525089

HSP71
Heat shock protein SSA1

1

19

High-throughput

0.445

High

546205

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

High-throughput

0.445

High

676334

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.445

High

742358

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

816394

HSP7E
Heat shock protein SSC3, mitochondrial

1

16

High-throughput

0.445

High

819745

SSB2
Ribosome-associated molecular chaperone SSB2

1

18

High-throughput

0.445

High

865235

GPI14
GPI mannosyltransferase 1

1

0

High-throughput

0.438

High

795203

NU170
Nucleoporin NUP170

1

4

High-throughput

0.437

High

812637

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

671099

SIS1
Protein SIS1

1

9

High-throughput

0.407

High

750300

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

64279

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

1044732

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

736724

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025