HitPredict

Interactor 1: K1C15 (P19012)
Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)
Gene: KRT15

Interactor 2: TCHP (Q9BT92)
Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein)
Gene: TCHP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	25416956, 16189514, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 456 Hs			1 498
+	Hs
		445110 K1C16_HUMAN (101-418): 1.73e-155: 451: 76.10		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		359403 K1C14_HUMAN (103-454): 9.83e-146: 425: 69.58		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		444469 K1C19_HUMAN (59-414): 3.71e-140: 409: 64.89		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		280707 KRT34_HUMAN (99-417): 5.45e-120: 357: 56.56		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		318873 K2C75_HUMAN (2-429): 1.43e-95: 300: 23.99		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		724787 K1C17_HUMAN (98-454): 6.71e-140: 409: 68.91		MYH9_HUMAN (12-482): 7.23e-12: 70.1: 12.68
+	Hs
		725143 K1C17_HUMAN (98-454): 6.71e-140: 409: 68.91		MYH10_HUMAN (13-495): 1.16e-11: 69.7: 10.77
+	Hs
		1055193 K1H2_HUMAN (1-426): 2.05e-80: 257: 47.18		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		1270301 KRT35_HUMAN (14-417): 3.65e-80: 257: 49.75		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		531622 K2C5_HUMAN (70-420): 2.21e-78: 256: 25.57		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		359528 K2C6A_HUMAN (70-436): 1.05e-77: 253: 24.19		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		1071336 K1H1_HUMAN (99-417): 4.47e-126: 374: 57.81		CFA53_HUMAN (141-495): 4.49e-11: 67: 14.37
+	Hs
		1071283 K1H1_HUMAN (99-417): 4.47e-126: 374: 57.81		GG6L2_HUMAN (16-365): 7.73e-09: 60.5: 13.39
+	Hs
		1055068 KT33B_HUMAN (99-417): 1.85e-122: 364: 57.19		GG6L2_HUMAN (16-365): 7.73e-09: 60.5: 13.39
+	Hs
		280692 KRT34_HUMAN (99-417): 5.45e-120: 357: 56.56		CFA53_HUMAN (141-495): 4.49e-11: 67: 14.37
+	Hs
		1189645 K1C27_HUMAN (45-451): 2.02e-115: 348: 53.11		CP250_HUMAN (22-497): 3.85e-11: 68.2: 15.21