HitPredict

Interactor 1: K2C4 (P19013)
Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Type-II keratin Kb4)
Gene: KRT4

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	30021884, 33961781
Identification Methods	cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 520 Hs			1 2115
+	Hs
		1061167 K2C78_HUMAN (71-481): 5.46e-140: 415: 60.38		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		318809 K2C75_HUMAN (2-464): 3.36e-94: 298: 64.29		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061108 K2C72_HUMAN (2-453): 6.1e-82: 265: 63.22		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		408987 K2C8_HUMAN (109-484): 5.4e-161: 467: 62.50		MYH1_HUMAN (1-831): 3.6e-35: 150: 12.27
+	Hs
		409080 K2C8_HUMAN (109-484): 5.4e-161: 467: 62.50		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		1068595 K2C78_HUMAN (71-481): 5.46e-140: 415: 60.38		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		444536 K2C7_HUMAN (94-464): 5.39e-147: 431: 66.04		GOGA4_HUMAN (5-528): 2.18e-12: 75: 11.24
+	Hs
		821662 K2C6C_HUMAN (1-469): 8.67e-79: 258: 62.63		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37