Interactor 1: EPOR (P19235)
Erythropoietin receptor (EPO-R)
Gene: EPOR

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10374881
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cbl_N~fn3, Cbl_N2~fn3, Cbl_N3~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0019221 - cytokine-mediated signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 508
Hs

1 906
+ Hs
+ Hs

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Last updated: 15 Jul 2024