HitPredict

Interactor 1: EPOR (P19235)
Erythropoietin receptor (EPO-R)
Gene: EPOR

Interactor 2: GRAP (Q13588)
GRB2-related adapter protein
Gene: GRAP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.681

Property	Details
Experiments	8647802
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 217
+	Hs
		581157 EPOR_HUMAN (1-508): 8.71e-145: 427: 100.00		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Mm
		540268 EPOR_MOUSE (1-508): 7.16e-140: 414: 81.69		GRB2_MOUSE (1-216): 3.23e-69: 212: 59.72
+	Hs
		433567 EPOR_HUMAN (1-508): 8.71e-145: 427: 100.00		LYN_HUMAN (4-204): 4.34e-36: 134: 25.58
+	Mm
		540265 EPOR_MOUSE (1-508): 7.16e-140: 414: 81.69		LYN_MOUSE (4-204): 6.53e-36: 133: 25.12
+	Hs
		548635 EPOR_HUMAN (1-508): 8.71e-145: 427: 100.00		VAV_HUMAN (2-60): 1.27e-16: 80: 33.90
+	Hs
		500956 GHR_HUMAN (6-482): 1.38e-87: 283: 15.10		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		522759 EPOR_HUMAN (1-508): 8.71e-145: 427: 100.00		SRC_HUMAN (141-214): 3.55e-11: 63.8: 21.05
+	Hs
		540459 IL2RB_HUMAN (17-488): 2.49e-64: 220: 17.52		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		562545 IL7RA_HUMAN (109-477): 4.76e-65: 219: 15.65		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		682260 IL2RG_HUMAN (15-351): 3.88e-59: 201: 17.35		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		924483 IL5RA_HUMAN (24-301): 7.09e-53: 186: 18.31		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		924809 CSF3R_HUMAN (14-425): 2.42e-50: 186: 13.92		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		500941 GHR_HUMAN (6-482): 1.38e-87: 283: 15.10		NCK1_HUMAN (5-145): 1.04e-23: 99: 35.47
+	Hs
		411578 IL2RB_HUMAN (17-488): 2.49e-64: 220: 17.52		LCK_HUMAN (4-204): 1.02e-41: 149: 26.98
+	Hs
		442875 CSF3R_HUMAN (14-425): 2.42e-50: 186: 13.92		HCK_HUMAN (4-158): 6.34e-52: 176: 32.74
+	Hs
		548629 PRLR_HUMAN (40-499): 4.21e-85: 276: 18.03		VAV_HUMAN (2-60): 1.27e-16: 80: 33.90
+	Hs
		560471 PRLR_HUMAN (40-499): 4.21e-85: 276: 18.03		VAV2_HUMAN (3-56): 5.17e-12: 66.1: 34.55
+	Hs
		433961 CSF3R_HUMAN (14-425): 2.42e-50: 186: 13.92		LYN_HUMAN (4-204): 4.34e-36: 134: 25.58
+	Mm
		411919 CSF3R_MOUSE (14-399): 4.44e-42: 162: 15.08		LCK_MOUSE (4-204): 4.57e-35: 131: 25.58
+	Hs
		411991 IL7RA_HUMAN (109-477): 4.76e-65: 219: 15.65		FYN_HUMAN (154-215): 1.46e-12: 67.7: 31.25