HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0017148 - negative regulation of translation GO:0042731 - PH domain binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 986
+	Hs
		171322 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		EPHB6_HUMAN (30-984): 0: 909: 40.10
+	Hs
		516373 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		UFO_HUMAN (268-928): 5.13e-150: 469: 23.72
+	Hs
		674526 PABP3_HUMAN (221-482): 6.38e-43: 166: 16.20		UFO_HUMAN (268-928): 5.13e-150: 469: 23.72
+	Hs
		674414 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		UFO_HUMAN (268-928): 5.13e-150: 469: 23.72
+	Rn
		86375 C1KE06_RAT (1-466): 7.43e-42: 162: 26.72		INSR_RAT (284-952): 7.97e-144: 465: 24.14
+	Rn
		88882 D4A233_RAT (222-482): 7.56e-42: 162: 15.90		INSR_RAT (284-952): 7.97e-144: 465: 24.14
+	Hs
		442776 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		HCK_HUMAN (573-879): 1.08e-66: 235: 41.29
+	Hs
		516342 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SRC_HUMAN (601-871): 2.14e-64: 229: 45.42
+	Hs
		523147 PABP3_HUMAN (221-482): 6.38e-43: 166: 16.20		SRC_HUMAN (601-871): 2.14e-64: 229: 45.42
+	Hs
		522960 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		SRC_HUMAN (601-871): 2.14e-64: 229: 45.42