Protein: INGR1
Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)

Gene: INGR1, IFNGR1
Organism: Homo sapiens
Interactions: 105
UniProt ID: P15260

Gene Ontology (top 5):
GO:0001774 - microglial cell activation
GO:0004896 - cytokine receptor activity
GO:0004906 - type II interferon receptor activity
GO:0005886 - plasma membrane
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

378411

IFNG
Interferon gamma

8

1

Small-scale

0.973

High

582207

NOTC3
Neurogenic locus notch homolog protein 3

2

1

High-throughput

0.811

High

582141

INGR2
Interferon gamma receptor 2

2

11

Small-scale

0.754

High

582143

STAT1
Signal transducer and activator of transcription 1-alpha/beta

6

14

Small-scale

0.717

High

582134

JAK1
Tyrosine-protein kinase JAK1

4

19

Small-scale

0.700

High

437624

HEPS
Serine protease hepsin

1

2

High-throughput

0.691

High

582131

INAR1
Interferon alpha/beta receptor 1

1

15

High-throughput

0.691

High

582187

SL9A6
Sodium/hydrogen exchanger 6

4

0

High-throughput

0.669

High

163231

TR10B
Tumor necrosis factor receptor superfamily member 10B

3

4

High-throughput

0.667

High

582173

RHOU
Rho-related GTP-binding protein RhoU

3

9

High-throughput

0.667

High

582188

RUSF1
RUS family member 1

3

1

High-throughput

0.665

High

541311

FGFR1
Fibroblast growth factor receptor 1

2

3

High-throughput

0.628

High

582139

BMR1A
Bone morphogenetic protein receptor type-1A

2

8

High-throughput

0.628

High

582167

CC50B
Cell cycle control protein 50B

2

1

High-throughput

0.628

High

582176

LRP10
Low-density lipoprotein receptor-related protein 10

2

3

High-throughput

0.628

High

582185

RAE1E
Retinoic acid early transcript 1E

2

4

High-throughput

0.628

High

582200

CD320
CD320 antigen

2

1

High-throughput

0.628

High

582144

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.618

High

582169

I20RB
Interleukin-20 receptor subunit beta

1

11

High-throughput

0.618

High

582205

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

3

1

Small-scale

0.609

High

582181

AGRG5
Adhesion G-protein coupled receptor G5

2

0

High-throughput

0.602

High

253285

JAK2
Tyrosine-protein kinase JAK2

2

19

Small-scale

0.584

High

375145

RASK
GTPase KRas

2

5

High-throughput

0.584

High

582153

RHOB
Rho-related GTP-binding protein RhoB

2

7

High-throughput

0.584

High

582162

STIM1
Stromal interaction molecule 1

2

0

High-throughput

0.580

High

582193

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

582201

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

582203

NINJ2
Ninjurin-2

2

0

High-throughput

0.580

High

582156

DLK1
Protein delta homolog 1

1

3

High-throughput

0.575

High

582194

NFIP1
NEDD4 family-interacting protein 1

2

2

High-throughput

0.574

High

140134

SDCB1
Syntenin-1

1

1

High-throughput

0.536

High

557062

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.536

High

582136

CALX
Calnexin

1

1

High-throughput

0.536

High

582137

RYK
Tyrosine-protein kinase RYK

1

7

High-throughput

0.536

High

582148

CTXN1
Cortexin-1

1

1

High-throughput

0.536

High

582159

NKG2E
NKG2-E type II integral membrane protein

1

2

High-throughput

0.536

High

582175

KCNKI
Potassium channel subfamily K member 18

1

1

High-throughput

0.536

High

582183

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.536

High

582199

CRLF2
Cytokine receptor-like factor 2

1

3

High-throughput

0.536

High

582208

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

1

High-throughput

0.536

High

533867

IRF1
Interferon regulatory factor 1

1

3

Small-scale

0.534

High

571647

HCLS1
Hematopoietic lineage cell-specific protein

1

0

High-throughput

0.513

High

582155

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

582177

T200A
Transmembrane protein 200A

1

0

High-throughput

0.513

High

582180

NRSN1
Neurensin-1

1

0

High-throughput

0.513

High

582184

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

0

High-throughput

0.513

High

582192

TMM74
Transmembrane protein 74

1

0

High-throughput

0.513

High

582189

LRIQ1
Leucine-rich repeat- and IQ domain-containing protein 1

1

2

High-throughput

0.489

High

189403

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

193197

SOCS1
Suppressor of cytokine signaling 1

1

8

Small-scale

0.479

High

217782

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

252654

TSN3
Tetraspanin-3

1

1

High-throughput

0.479

High

373755

RASN
GTPase NRas

1

4

High-throughput

0.479

High

374378

RASH
GTPase HRas

1

5

High-throughput

0.479

High

410579

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

15

High-throughput

0.479

High

466091

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

571547

IRF2
Interferon regulatory factor 2

1

3

Small-scale

0.479

High

582130

RHOQ
Rho-related GTP-binding protein RhoQ

1

8

High-throughput

0.479

High

582138

BASI
Basigin

1

2

High-throughput

0.479

High

582146

RND2
Rho-related GTP-binding protein RhoN

1

7

High-throughput

0.479

High

582149

RAC3
Ras-related C3 botulinum toxin substrate 3

1

7

High-throughput

0.479

High

582150

CDC42
Cell division control protein 42 homolog

1

8

High-throughput

0.479

High

582151

RHOA
Transforming protein RhoA

1

6

High-throughput

0.479

High

582154

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

High-throughput

0.479

High

582157

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

582160

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

582164

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

582165

RHOH
Rho-related GTP-binding protein RhoH

1

8

High-throughput

0.479

High

582179

PARP9
Protein mono-ADP-ribosyltransferase PARP9

1

1

Small-scale

0.479

High

582196

RHOJ
Rho-related GTP-binding protein RhoJ

1

8

High-throughput

0.479

High

582132

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

582133

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.458

High

582135

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

582158

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

582166

OCLN
Occludin

1

0

High-throughput

0.458

High

582182

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.458

High

582186

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

0

Small-scale

0.458

High

582202

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

582204

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

388362

B3AT
Band 3 anion transport protein

1

1

High-throughput

0.445

High

484037

PGFRB
Platelet-derived growth factor receptor beta

1

7

High-throughput

0.445

High

582140

TGFR2
TGF-beta receptor type-2

1

8

High-throughput

0.445

High

582170

ZNT10
Calcium/manganese antiporter SLC30A10

1

3

High-throughput

0.445

High

582178

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

3

High-throughput

0.445

High

582191

MF14A
Hippocampus abundant transcript 1 protein

1

2

High-throughput

0.445

High

582142

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.437

High

582209

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.437

High

190302

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.426

High

582145

NRAM2
Natural resistance-associated macrophage protein 2

1

0

High-throughput

0.426

High

582147

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

0

High-throughput

0.426

High

582163

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

582171

LHPL2
LHFPL tetraspan subfamily member 2 protein

1

0

High-throughput

0.426

High

582174

MOT9
Monocarboxylate transporter 9

1

0

High-throughput

0.426

High

582190

S45A3
Solute carrier family 45 member 3

1

0

High-throughput

0.426

High

582195

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.426

High

582210

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.426

High

582197

ZDH11
Palmitoyltransferase ZDHHC11

1

1

High-throughput

0.407

High

582161

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

582152

RB11A
Ras-related protein Rab-11A

2

0

High-throughput

0.305

High

582198

SACA1
Sperm acrosome membrane-associated protein 1

1

0

High-throughput

0.279

Low

582206

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

139809

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

576919

I23O1
Indoleamine 2,3-dioxygenase 1

1

0

Small-scale

0.249

Low

582168

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

582172

H32
Histone H3.2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025