HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: MOES (P26038)
Moesin (Membrane-organizing extension spike protein)
Gene: MSN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 15659383, 8248180, 35271311, 38334954, 39358380, 26496610, 29568061, 34079125, 7579708, 33961781, 35235311, 34349018, 37071682, 31839598, unassigned1655
Identification Methods biochemical, pull down, affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ERM_C~ERM_C, ERM_C~FERM_C, ERM_C~FERM_M, ERM_helical~FERM_N, FERM_C~FERM_C, FERM_C~FERM_M, FERM_C~FERM_N, FERM_M~FERM_M, FERM_M~FERM_N, FERM_N~FERM_N
Common GO terms GO:0001931 - uropod
GO:0003779 - actin binding
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 23 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 586
Hs

1 577
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+ Ce
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 11Aug2025