Interactor 1: ELK1 (P19419)
ETS domain-containing protein Elk-1
Gene: ELK1

Interactor 2: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 8586671, 14557262, 11532856, 12594221, 34497368, 10644696, 20371703, 21655091, 12220533, 11279280, 12551925, 15782123, 15655247, 11857080, 9130707, 8846788, 15967991, 16291755, 12788955
Identification Methods pull down, enzymatic study, affinity chromatography technology, protein kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 428
Hs

1 360
+ Hs
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+ Rn
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+ Rn
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+ Dm
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+ Ce
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024