Interactor 1: ERCC3 (P19447)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB (TFIIH subunit XPB) (EC 5.6.2.4) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA 3'-5' helicase/translocase XPB) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
Gene: ERCC3

Interactor 2: TF2H5 (Q6ZYL4)
General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) (TFIIH subunit p8)
Gene: GTF2H5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.90 0.925

The method score is based on:

Property Details
Experiments 28514442, 26340423, 15220921, 33961781, 26496610, 24981860, 16669699, 19172752
Identification Methods affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ERCC3_RAD25_C~Tfb5
Common GO terms GO:0000439 - transcription factor TFIIH core complex
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0005675 - transcription factor TFIIH holo complex
GO:0006289 - nucleotide-excision repair
and 2 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024