HitPredict

Interactor 1: AREG (P15514)
Amphiregulin (AR) (Colorectum cell-derived growth factor) (CRDGF)
Gene: AREG

Interactor 2: S10A4 (P26447)
Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4)
Gene: S100A4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	19740107, 30083275
Identification Methods	far western blotting, surface plasmon resonance, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 252 Hs			1 101
+	Hs
		584635 AREG_HUMAN (1-252): 3.4e-111: 321: 100.00		S10A2_HUMAN (1-97): 1.09e-36: 121: 60.83
+	Hs
		584636 AREG_HUMAN (1-252): 3.4e-111: 321: 100.00		S10A5_HUMAN (1-90): 1.46e-25: 93: 53.33
+	Hs
		686858 HBEGF_HUMAN (100-247): 9.6e-37: 130: 29.53		S10A4_HUMAN (1-101): 5.67e-40: 129: 100.00
+	Hs
		686805 NRG1_HUMAN (123-252): 2.65e-28: 114: 18.52		S10A4_HUMAN (1-101): 5.67e-40: 129: 100.00
+	Hs
		686783 BTC_HUMAN (119-220): 5.42e-29: 109: 19.09		S10A4_HUMAN (1-101): 5.67e-40: 129: 100.00
+	Hs
		754558 BTC_HUMAN (119-220): 5.42e-29: 109: 19.09		S10A3_HUMAN (1-98): 1.27e-35: 118: 45.92
+	Hs
		376582 EGF_HUMAN (140-187): 8.7e-09: 57.5: 36.74		S10A4_HUMAN (1-101): 5.67e-40: 129: 100.00