Interactor 1: SPEE (P19623)
Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)
Gene: SRM

Interactor 2: SPEE (P19623)
Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)
Gene: SRM

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 32296183, 31515488, 29892012, unassigned1304, 17585781
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Spermine_synt_N~Spermine_synt_N, Spermine_synt_N~Spermine_synth, Spermine_synth~Spermine_synth
Common GO terms GO:0004766 - spermidine synthase activity
GO:0005829 - cytosol
GO:0006595 - polyamine metabolic process
GO:0008295 - spermidine biosynthetic process
GO:0042803 - protein homodimerization activity
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 302
Hs

1 302
+ At
+ At
+ At
+ Sp
+ At
+ At
+ Sc
+ At
+ Ec

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Last updated: 15 Jul 2024