HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: IKBB (Q15653)
NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9)
Gene: NFKBIB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 27609421, 35140242, 35271311, 14743216
Identification Methods affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank, Ank~Ank_2, Ank~Ank_4, Ank_2~Ank_2, Ank_2~Ank_4, Ank~RHD_dimer, Ank_2~RHD_dimer
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 968
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Last updated: 15 Jul 2024