HitPredict

Interactor 1: BIP (P20029)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: Hspa5

Interactor 2: HYOU1 (Q9JKR6)
Hypoxia up-regulated protein 1 (GRP-170) (140 kDa Ca(2+)-binding protein) (CBP-140)
Gene: HYOU1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24218449
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP70~HSP70
Common GO terms GO:0005524 - ATP binding
GO:0005576 - extracellular region
GO:0005788 - endoplasmic reticulum lumen
GO:0005790 - smooth endoplasmic reticulum
GO:0030968 - endoplasmic reticulum unfolded protein response
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 655
Mm

1 999
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024