HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: BRF2 (Q9HAW0)
Transcription factor IIIB 50 kDa subunit (TFIIIB50) (hTFIIIB50) (B-related factor 2) (BRF-2) (hBRFU)
Gene: BRF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 11564744, 33961781, 17353931
Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006352 - DNA-templated transcription initiation
GO:0006367 - transcription initiation at RNA polymerase II promoter
GO:0016251 - RNA polymerase II general transcription initiation factor activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 339
Hs

1 419
+ Hs
+ Hs
+ Mm
+ Sc
+ Sp
+ Dm
+ Dm
+ Dm
+ At
+ Dm
+ Hs
+ Sc
+ Pf

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Last updated: 15 Jul 2024