HitPredict

Interactor 1: IF2B (P20042)
Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF2-beta)
Gene: EIF2S2

Interactor 2: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 333 Hs			1 1356
+	Hs
		572584 IF2B_HUMAN (1-333): 4.04e-148: 422: 100.00		VGFR1_HUMAN (1-131): 5.1e-20: 99.3: 13.38
+	Hs
		588847 IF2B_HUMAN (1-333): 4.04e-148: 422: 100.00		FLT3_HUMAN (40-555): 7.17e-20: 98.5: 16.22
+	Hs
		588836 IF2B_HUMAN (1-333): 4.04e-148: 422: 100.00		FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90
+	Hs
		507846 IF2B_HUMAN (1-333): 4.04e-148: 422: 100.00		FGFR1_HUMAN (1-169): 8.34e-17: 88.1: 13.54
+	Hs
		588845 IF2B_HUMAN (1-333): 4.04e-148: 422: 100.00		VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93