Protein: PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 2) (1-AGP acyltransferase 2) (1-AGPAT 2) (Lysophosphatidic acid acyltransferase beta) (LPAAT-beta)

Gene: PLCB, AGPAT2
Organism: Homo sapiens
Interactions: 77
UniProt ID: O15120

Gene Ontology (top 5):
GO:0001819 - positive regulation of cytokine production
GO:0001961 - positive regulation of cytokine-mediated signaling pathway
GO:0003841 - 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

178538

EAA3
Excitatory amino acid transporter 3

3

4

High-throughput

0.643

High

178535

APJ
Apelin receptor

2

7

High-throughput

0.628

High

178577

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

2

18

High-throughput

0.628

High

178529

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

2

16

High-throughput

0.601

High

178556

S22AG
Solute carrier family 22 member 16

2

10

High-throughput

0.601

High

178525

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

178532

H13
Histone H1.3

2

1

High-throughput

0.549

High

165858

FFAR1
Free fatty acid receptor 1

1

11

High-throughput

0.536

High

178518

GP182
G-protein coupled receptor 182

1

17

High-throughput

0.536

High

178521

RAMP3
Receptor activity-modifying protein 3

1

7

High-throughput

0.536

High

178526

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.536

High

178527

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

7

High-throughput

0.536

High

178530

GPIX
Platelet glycoprotein IX

1

4

High-throughput

0.536

High

178533

FPR2
N-formyl peptide receptor 2

1

14

High-throughput

0.536

High

178534

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

10

High-throughput

0.536

High

178542

CAV2
Caveolin-2

1

2

High-throughput

0.536

High

178544

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.536

High

178545

AT12A
Potassium-transporting ATPase alpha chain 2

1

16

High-throughput

0.536

High

178550

P2RY6
P2Y purinoceptor 6

1

15

High-throughput

0.536

High

178552

S39AC
Zinc transporter ZIP12

1

19

High-throughput

0.536

High

178553

TTMP
TPA-induced transmembrane protein

1

3

High-throughput

0.536

High

178554

T184A
Transmembrane protein 184A

1

1

High-throughput

0.536

High

178557

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

9

High-throughput

0.536

High

178565

AQP3
Aquaporin-3

1

4

High-throughput

0.536

High

178568

TSN17
Tetraspanin-17

1

20

High-throughput

0.536

High

178569

M4A4A
Membrane-spanning 4-domains subfamily A member 4A

1

1

High-throughput

0.536

High

178570

SEC62
Translocation protein SEC62

1

6

High-throughput

0.536

High

178572

SGMR1
Sigma non-opioid intracellular receptor 1

1

1

High-throughput

0.536

High

178573

RNF5
E3 ubiquitin-protein ligase RNF5

1

2

High-throughput

0.536

High

178575

UN93B
Protein unc-93 homolog B1

1

3

High-throughput

0.536

High

178578

TTYH1
Protein tweety homolog 1

1

5

High-throughput

0.536

High

178581

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

2

High-throughput

0.536

High

178584

CLC2D
C-type lectin domain family 2 member D

1

14

High-throughput

0.536

High

178589

PCDB7
Protocadherin beta-7

1

2

High-throughput

0.536

High

178590

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.536

High

178549

CLN3
Battenin

1

0

High-throughput

0.513

High

178551

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

178563

GPBAR
G-protein coupled bile acid receptor 1

1

0

High-throughput

0.513

High

178566

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.513

High

178520

MFS11
UNC93-like protein MFSD11

1

3

High-throughput

0.489

High

178546

EVA1C
Protein eva-1 homolog C

1

1

High-throughput

0.489

High

178560

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

3

High-throughput

0.489

High

178588

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

4

High-throughput

0.489

High

178576

ABCG8
ATP-binding cassette sub-family G member 8

1

2

High-throughput

0.481

High

178519

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

178580

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.479

High

178585

S12A6
Solute carrier family 12 member 6

1

8

Small-scale

0.479

High

178583

S23A2
Solute carrier family 23 member 2

1

0

High-throughput

0.460

High

178524

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

178528

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.445

High

178537

EAA2
Excitatory amino acid transporter 2

1

4

High-throughput

0.445

High

178539

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

18

High-throughput

0.445

High

178547

CXCR4
C-X-C chemokine receptor type 4

1

11

High-throughput

0.445

High

178558

STING
Stimulator of interferon genes protein

1

6

Small-scale

0.445

High

178561

S7A14
Solute carrier family 7 member 14

1

11

High-throughput

0.445

High

178562

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

5

High-throughput

0.445

High

178564

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

1

High-throughput

0.445

High

178571

CHP1
Calcineurin B homologous protein 1

1

3

High-throughput

0.445

High

178579

S39A2
Zinc transporter ZIP2

1

19

High-throughput

0.445

High

178540

GUAA
GMP synthase [glutamine-hydrolyzing]

1

1

High-throughput

0.439

High

178582

PHRF1
PHD and RING finger domain-containing protein 1

1

1

High-throughput

0.439

High

178586

PHF11
PHD finger protein 11

1

2

High-throughput

0.439

High

178531

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

178559

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

49607

T120B
Transmembrane protein 120B

1

3

High-throughput

0.407

High

104065

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

178543

MSH6
DNA mismatch repair protein Msh6

1

1

High-throughput

0.407

High

178522

TNF13
Tumor necrosis factor ligand superfamily member 13

1

0

High-throughput

0.279

Low

178523

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.279

Low

178536

HPCL1
Hippocalcin-like protein 1

1

0

High-throughput

0.279

Low

178555

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

178567

F131C
Protein FAM131C

1

0

High-throughput

0.279

Low

178574

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.279

Low

177136

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

0

High-throughput

0.251

Low

178541

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.249

Low

178548

H4
Histone H4

1

0

High-throughput

0.249

Low

178587

INTU
Protein inturned

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025