Interactor 1: PGTB2 (P20133)
Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Type II protein geranyl-geranyltransferase subunit beta) (PGGT) (YPT1/SEC4 proteins geranylgeranyltransferase subunit beta)
Gene: BET2

Interactor 2: RAEP (P32864)
Rab proteins geranylgeranyltransferase component A (Rab escort protein) (REP)
Gene: MRS6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 12022885, 8183917, 18719252
Identification Methods fluorescent resonance energy transfer, pull down, enzymatic study, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005968 - Rab-protein geranylgeranyltransferase complex
GO:0006612 - protein targeting to membrane
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0018344 - protein geranylgeranylation
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 325
Sc

1 603
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024