Protein: PARP9
Protein mono-ADP-ribosyltransferase PARP9 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein) (Poly [ADP-ribose] polymerase 9) (PARP-9)

Gene: PARP9
Organism: Homo sapiens
Interactions: 35
UniProt ID: Q8IXQ6

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002230 - positive regulation of defense response to virus by host
GO:0003714 - transcription corepressor activity
GO:0003950 - NAD+ poly-ADP-ribosyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1312889

DTX3L
E3 ubiquitin-protein ligase DTX3L

12

7

Small-scale

0.759

High

1192947

PAR14
Protein mono-ADP-ribosyltransferase PARP14

1

15

Small-scale

0.618

High

838133

STAT1
Signal transducer and activator of transcription 1-alpha/beta

2

7

Small-scale

0.584

High

1312891

RN166
E3 ubiquitin-protein ligase RNF166

1

17

High-throughput

0.536

High

1312892

SORT
Sortilin

1

2

High-throughput

0.536

High

273077

CLU
Clustered mitochondria protein homolog

1

3

High-throughput

0.515

High

1163045

H2B2E
Histone H2B type 2-E

1

20

Small-scale

0.501

High

253363

JAK2
Tyrosine-protein kinase JAK2

1

8

Small-scale

0.479

High

449749

H2B1J
Histone H2B type 1-J

1

20

Small-scale

0.479

High

487509

PARP1
Poly [ADP-ribose] polymerase 1

1

19

Small-scale

0.479

High

537480

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

582179

INGR1
Interferon gamma receptor 1

1

1

Small-scale

0.479

High

589112

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

658732

JAK1
Tyrosine-protein kinase JAK1

1

11

Small-scale

0.479

High

695896

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

714255

PML
Protein PML

1

14

High-throughput

0.479

High

768605

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

913146

STAT2
Signal transducer and activator of transcription 2

1

7

Small-scale

0.479

High

1113635

CUL3
Cullin-3

1

12

High-throughput

0.479

High

1141768

EEA1
Early endosome antigen 1

1

7

High-throughput

0.479

High

1227027

A16L1
Autophagy-related protein 16-1

1

16

High-throughput

0.479

High

1254554

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1312888

CGAS
Cyclic GMP-AMP synthase

1

4

High-throughput

0.479

High

1312890

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

391339

FRIL
Ferritin light chain

1

2

High-throughput

0.445

High

848797

MAGAA
Melanoma-associated antigen 10

1

5

High-throughput

0.445

High

944399

SYJ2B
Synaptojanin-2-binding protein

1

4

High-throughput

0.445

High

1094927

TRAF3
TNF receptor-associated factor 3

1

18

High-throughput

0.445

High

1312894

PAR12
Protein mono-ADP-ribosyltransferase PARP12

1

11

High-throughput

0.445

High

384698

CRYAB
Alpha-crystallin B chain

1

0

High-throughput

0.426

High

896412

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.426

High

402964

ANXA1
Annexin A1

1

4

Small-scale

0.408

High

1312893

S35A5
UDP-sugar transporter protein SLC35A5

1

2

High-throughput

0.407

High

1312895

SL9A8
Sodium/hydrogen exchanger 8

1

2

High-throughput

0.407

High

1254108

RBM43
RNA-binding protein 43

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025