Interactor 1: AL5AP (P20292)
Arachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein)
Gene: ALOX5AP

Interactor 2: AL5AP (P20292)
Arachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein)
Gene: ALOX5AP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 17600184
Identification Methods x-ray crystallography
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MAPEG~MAPEG
Common GO terms GO:0002540 - leukotriene production involved in inflammatory response
GO:0002675 - positive regulation of acute inflammatory response
GO:0004051 - arachidonate 5-lipoxygenase activity
GO:0004364 - glutathione transferase activity
GO:0004464 - leukotriene-C4 synthase activity
and 14 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 161
Hs

1 161
+ Rn
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024