Protein: MET
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)

Gene: MET
Organism: Mus musculus
Interactions: 143
UniProt ID: P16056

Gene Ontology (top 5):
GO:0001889 - liver development
GO:0001890 - placenta development
GO:0004672 - protein kinase activity
GO:0005008 - hepatocyte growth factor receptor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

591103

VGFR2
Vascular endothelial growth factor receptor 2

1

20

Small-scale

0.665

High

591153

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.646

High

591189

GAB1
GRB2-associated-binding protein 1

1

19

Small-scale

0.590

High

49180

A0JP53
Diacylglycerol kinase

1

6

High-throughput

0.575

High

59105

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

20

High-throughput

0.575

High

59359

A2AI78
Connector enhancer of kinase suppressor of ras 2

1

20

High-throughput

0.575

High

60070

KALRN
Kalirin

1

8

High-throughput

0.575

High

590996

KPCE
Protein kinase C epsilon type

1

8

High-throughput

0.575

High

591098

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

20

High-throughput

0.575

High

591102

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

20

High-throughput

0.575

High

591104

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.575

High

591106

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.575

High

591107

CDK5
Cyclin-dependent kinase 5

1

11

High-throughput

0.575

High

591108

EPHB2
Ephrin type-B receptor 2

1

19

High-throughput

0.575

High

591115

PLXA1
Plexin-A1

1

19

High-throughput

0.575

High

591118

NEO1
Neogenin

1

18

High-throughput

0.575

High

591119

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.575

High

591120

MARK3
MAP/microtubule affinity-regulating kinase 3

1

5

High-throughput

0.575

High

591123

TRIO
Triple functional domain protein

1

7

High-throughput

0.575

High

591125

Q2NKI4
Protein kinase C

1

12

High-throughput

0.575

High

591128

WNK2
Serine/threonine-protein kinase WNK2

1

17

High-throughput

0.575

High

591129

PLXD1
Plexin-D1

1

20

High-throughput

0.575

High

591132

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

10

High-throughput

0.575

High

591135

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

11

High-throughput

0.575

High

591138

Q4VA93
Protein kinase C

1

12

High-throughput

0.575

High

591140

LMTK3
Serine/threonine-protein kinase LMTK3

1

20

High-throughput

0.575

High

591142

ACV1B
Activin receptor type-1B

1

20

High-throughput

0.575

High

591148

DLG4
Disks large homolog 4

1

16

High-throughput

0.575

High

591150

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

4

High-throughput

0.575

High

591159

PLXA4
Plexin-A4

1

19

High-throughput

0.575

High

591161

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

1

17

High-throughput

0.575

High

591177

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

4

High-throughput

0.575

High

591185

PLEC
Plectin

1

10

High-throughput

0.575

High

591186

DREB
Drebrin

1

9

High-throughput

0.575

High

591187

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4

1

14

High-throughput

0.575

High

85884

B8QI36
Liprin-alpha 4

1

4

High-throughput

0.514

High

92691

D3YZU5
SH3 and multiple ankyrin repeat domains protein 1

1

8

High-throughput

0.514

High

107103

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

10

High-throughput

0.514

High

591099

COF1
Cofilin-1

1

1

High-throughput

0.514

High

591110

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

20

High-throughput

0.514

High

591112

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.514

High

591131

SRBS2
Sorbin and SH3 domain-containing protein 2

1

20

High-throughput

0.514

High

591137

UN13A
Protein unc-13 homolog A

1

7

High-throughput

0.514

High

591154

MTMR5
Myotubularin-related protein 5

1

3

High-throughput

0.514

High

591183

LGI1
Leucine-rich glioma-inactivated protein 1

1

17

High-throughput

0.514

High

591193

ATRN
Attractin

1

10

High-throughput

0.514

High

104741

F6Z0Z5
Rad and gem related GTP binding protein 2

1

0

High-throughput

0.481

High

104457

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

15

High-throughput

0.479

High

591133

GRM5
Metabotropic glutamate receptor 5

1

5

High-throughput

0.479

High

59301

A2AG41
Stomatin-like protein 2, mitochondrial

1

6

High-throughput

0.445

High

73085

SCN2A
Sodium channel protein type 2 subunit alpha

1

11

High-throughput

0.445

High

73893

PYR1
Multifunctional protein CAD

1

5

High-throughput

0.445

High

97850

E9Q175
Unconventional myosin-VI

1

5

High-throughput

0.445

High

97909

PI4KA
Phosphatidylinositol 4-kinase alpha

1

6

High-throughput

0.445

High

98173

E9Q6A9
Catenin beta 1

1

15

High-throughput

0.445

High

98310

E9QK16
Protocadherin Fat 3

1

20

High-throughput

0.445

High

107176

F8VQE2
Kinesin family member 21B

1

4

High-throughput

0.445

High

109254

ANK3
Ankyrin-3

1

4

High-throughput

0.445

High

236375

AP3D1
AP-3 complex subunit delta-1

1

4

High-throughput

0.445

High

267011

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

9

High-throughput

0.445

High

312106

S4A4
Electrogenic sodium bicarbonate cotransporter 1

1

9

High-throughput

0.445

High

549489

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

1

High-throughput

0.445

High

591100

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

9

High-throughput

0.445

High

591105

AINX
Alpha-internexin

1

6

High-throughput

0.445

High

591113

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

5

High-throughput

0.445

High

591117

GRM1
Metabotropic glutamate receptor 1

1

5

High-throughput

0.445

High

591121

NF1
Neurofibromin

1

15

High-throughput

0.445

High

591143

CAC1E
Voltage-dependent R-type calcium channel subunit alpha-1E

1

11

High-throughput

0.445

High

591146

HS105
Heat shock protein 105 kDa

1

20

High-throughput

0.445

High

591151

NEB2
Neurabin-2

1

20

High-throughput

0.445

High

591152

MYH14
Myosin-14

1

4

High-throughput

0.445

High

591155

PITM2
Membrane-associated phosphatidylinositol transfer protein 2

1

1

High-throughput

0.445

High

591157

MADD
MAP kinase-activating death domain protein

1

1

High-throughput

0.445

High

591160

L2GL1
Lethal(2) giant larvae protein homolog 1

1

2

High-throughput

0.445

High

591167

SYN3
Synapsin-3

1

2

High-throughput

0.445

High

591171

MYH9
Myosin-9

1

4

High-throughput

0.445

High

591172

S12A5
Solute carrier family 12 member 5

1

10

High-throughput

0.445

High

591173

PCDAA
Protocadherin alpha-10

1

14

High-throughput

0.445

High

591174

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

8

High-throughput

0.445

High

591184

SV2A
Synaptic vesicle glycoprotein 2A

1

1

High-throughput

0.445

High

591195

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

1

20

High-throughput

0.445

High

591101

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.437

High

591141

ASTN1
Astrotactin-1

1

0

High-throughput

0.426

High

591175

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.426

High

591178

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.426

High

59039

TANC2
Protein TANC2

1

8

High-throughput

0.407

High

59341

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

1

High-throughput

0.407

High

59345

A2AHC4
Calmodulin regulated spectrin-associated protein 1

1

1

High-throughput

0.407

High

59678

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

High-throughput

0.407

High

59695

A2ANL9
Teneurin-1

1

8

High-throughput

0.407

High

92693

D3YZY0
Actin, gamma 2, smooth muscle, enteric

1

3

High-throughput

0.407

High

97839

E9Q030
Actin-binding LIM protein 1

1

1

High-throughput

0.407

High

98090

E9Q5E1
Protocadherin-19

1

19

High-throughput

0.407

High

98091

E9Q5F6
Polyubiquitin-C

1

7

High-throughput

0.407

High

98226

E9Q852
Afadin

1

12

High-throughput

0.407

High

98352

E9QMC2
Metabotropic glutamate receptor 5

1

5

High-throughput

0.407

High

104677

F6U8U1
Intersectin 1

1

20

High-throughput

0.407

High

104770

F7ADT6
GTPase activating protein and VPS9 domains 1

1

5

High-throughput

0.407

High

108287

G3X922
DnaJ heat shock protein family

1

11

High-throughput

0.407

High

116258

H3BJU7
Rho guanine nucleotide exchange factor 2

1

20

High-throughput

0.407

High

116264

H3BLF7
Guanine nucleotide binding protein

1

7

High-throughput

0.407

High

117089

J3QP81
CLIP-associating protein 1

1

3

High-throughput

0.407

High

204214

DPYL4
Dihydropyrimidinase-related protein 4

1

5

High-throughput

0.407

High

205693

PITM1
Membrane-associated phosphatidylinositol transfer protein 1

1

1

High-throughput

0.407

High

470790

NFM
Neurofilament medium polypeptide

1

8

High-throughput

0.407

High

591109

RHG39
Rho GTPase-activating protein 39

1

11

High-throughput

0.407

High

591111

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

3

High-throughput

0.407

High

591114

RACK1
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.407

High

591116

G3BP2
Ras GTPase-activating protein-binding protein 2

1

3

High-throughput

0.407

High

591122

CLUS
Clusterin

1

6

High-throughput

0.407

High

591124

GRM2
Metabotropic glutamate receptor 2

1

5

High-throughput

0.407

High

591126

Q3TWV4
AP-2 complex subunit mu

1

4

High-throughput

0.407

High

591127

TPPC9
Trafficking protein particle complex subunit 9

1

2

High-throughput

0.407

High

591130

TEN4
Teneurin-4

1

9

High-throughput

0.407

High

591136

Q4FE56
ubiquitinyl hydrolase 1

1

7

High-throughput

0.407

High

591139

Q5SVG5
AP complex subunit beta

1

5

High-throughput

0.407

High

591144

CTNA2
Catenin alpha-2

1

9

High-throughput

0.407

High

591145

FSCN1
Fascin

1

3

High-throughput

0.407

High

591149

RHG23
Rho GTPase-activating protein 23

1

14

High-throughput

0.407

High

591156

LARP1
La-related protein 1

1

2

High-throughput

0.407

High

591158

C170B
Centrosomal protein of 170 kDa protein B

1

4

High-throughput

0.407

High

591162

FAT3
Protocadherin Fat 3

1

20

High-throughput

0.407

High

591164

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

7

High-throughput

0.407

High

591165

NAV1
Neuron navigator 1

1

4

High-throughput

0.407

High

591166

DOCK3
Dedicator of cytokinesis protein 3

1

6

High-throughput

0.407

High

591168

AGRL2
Adhesion G protein-coupled receptor L2

1

7

High-throughput

0.407

High

591169

HECW1
E3 ubiquitin-protein ligase HECW1

1

13

High-throughput

0.407

High

591170

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

3

High-throughput

0.407

High

591179

SNX20
Sorting nexin-20

1

10

High-throughput

0.407

High

591181

CPNE8
Copine-8

1

4

High-throughput

0.407

High

591182

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

7

High-throughput

0.407

High

591188

MAP1A
Microtubule-associated protein 1A

1

9

High-throughput

0.407

High

591190

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

17

High-throughput

0.407

High

591191

SYT11
Synaptotagmin-11

1

1

High-throughput

0.407

High

591192

TEN2
Teneurin-2

1

8

High-throughput

0.407

High

591194

CLIP2
CAP-Gly domain-containing linker protein 2

1

5

High-throughput

0.407

High

97844

E9Q0I8
Homer scaffolding protein 1

1

0

High-throughput

0.232

Low

98230

FRY
Protein furry homolog

1

0

High-throughput

0.232

Low

591134

ELMD1
ELMO domain-containing protein 1

1

0

High-throughput

0.232

Low

591147

SERA
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.232

Low

591163

VP13C
Intermembrane lipid transfer protein VPS13C

1

0

High-throughput

0.232

Low

591176

T132A
Transmembrane protein 132A

1

0

High-throughput

0.232

Low

591180

CMIP
C-Maf-inducing protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025