Protein: SOX4
Transcription factor SOX-4

Gene: SOX4
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q06945

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

958886

TFAM
Transcription factor A, mitochondrial

1

19

High-throughput

0.618

High

989539

PB1
Protein polybromo-1

1

20

High-throughput

0.618

High

386593

P53
Cellular tumor antigen p53

1

13

Small-scale

0.589

High

132833

SDCB1
Syntenin-1

1

5

Small-scale

0.561

High

268453

BAF
Barrier-to-autointegration factor

1

2

Small-scale

0.552

High

930166

UBC9
SUMO-conjugating enzyme UBC9

1

11

Small-scale

0.552

High

214560

MYO1B
Unconventional myosin-Ib

1

5

High-throughput

0.536

High

989526

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.515

High

989534

ACTBL
Beta-actin-like protein 2

1

5

High-throughput

0.515

High

975642

LMNB2
Lamin-B2

1

18

Small-scale

0.504

High

154022

TERT
Telomerase reverse transcriptase

1

1

High-throughput

0.501

High

160530

AURKA
Aurora kinase A

1

14

High-throughput

0.501

High

346609

MYC
Myc proto-oncogene protein

1

18

High-throughput

0.501

High

350103

RASK
GTPase KRas

1

5

High-throughput

0.501

High

585906

WT1
Wilms tumor protein

1

20

High-throughput

0.501

High

598466

NF1
Neurofibromin

1

3

High-throughput

0.501

High

681805

AKT1
RAC-alpha serine/threonine-protein kinase

1

9

High-throughput

0.501

High

719458

MERL
Merlin

1

14

High-throughput

0.501

High

790756

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

16

High-throughput

0.501

High

846943

SMCA4
Transcription activator BRG1

1

20

High-throughput

0.501

High

989542

TSC1
Hamartin

1

11

High-throughput

0.501

High

989547

NSD3
Histone-lysine N-methyltransferase NSD3

1

20

High-throughput

0.501

High

989551

DACH1
Dachshund homolog 1

1

3

High-throughput

0.501

High

989552

FZR1
Fizzy-related protein homolog

1

17

High-throughput

0.501

High

896050

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.500

High

989555

PDIP2
Polymerase delta-interacting protein 2

1

1

High-throughput

0.500

High

989556

STRAP
Serine-threonine kinase receptor-associated protein

1

20

High-throughput

0.500

High

270781

FOXH1
Forkhead box protein H1

1

20

Small-scale

0.481

High

275494

CAN15
Calpain-15

1

12

Small-scale

0.481

High

989535

CTR9
RNA polymerase-associated protein CTR9 homolog

1

12

Small-scale

0.481

High

989545

MNT
Max-binding protein MNT

1

20

Small-scale

0.481

High

989531

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.480

High

164863

SC16A
Protein transport protein Sec16A

1

20

High-throughput

0.479

High

229662

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

3

High-throughput

0.479

High

267755

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

20

High-throughput

0.479

High

620486

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

20

Small-scale

0.479

High

657335

ABCD3
ATP-binding cassette sub-family D member 3

1

1

High-throughput

0.479

High

683069

CASPE
Caspase-14

1

2

High-throughput

0.479

High

708425

MCM4
DNA replication licensing factor MCM4

1

8

High-throughput

0.479

High

764634

CUX1
Homeobox protein cut-like 1

1

20

High-throughput

0.479

High

832396

MCM2
DNA replication licensing factor MCM2

1

10

High-throughput

0.479

High

850013

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

10

High-throughput

0.479

High

989527

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

4

High-throughput

0.479

High

989528

PWP1
Periodic tryptophan protein 1 homolog

1

20

High-throughput

0.479

High

989529

MCM6
DNA replication licensing factor MCM6

1

10

High-throughput

0.479

High

989530

TAF5
Transcription initiation factor TFIID subunit 5

1

20

Small-scale

0.479

High

989532

GLO2
Hydroxyacylglutathione hydrolase, mitochondrial

1

1

High-throughput

0.479

High

989533

FIL1L
Filamin A-interacting protein 1-like

1

9

High-throughput

0.479

High

989538

TAD2B
Transcriptional adapter 2-beta

1

11

High-throughput

0.479

High

989543

CBP
CREB-binding protein

1

20

Small-scale

0.479

High

989544

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

989546

PDIP3
Polymerase delta-interacting protein 3

1

7

High-throughput

0.479

High

989548

GTPB4
GTP-binding protein 4

1

6

High-throughput

0.479

High

989550

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

2

High-throughput

0.479

High

989554

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

8

Small-scale

0.479

High

989557

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

High-throughput

0.479

High

243002

EDF1
Endothelial differentiation-related factor 1

1

0

Small-scale

0.460

High

392957

IGF1
Insulin-like growth factor I

1

0

Small-scale

0.460

High

584294

TNNI3
Troponin I, cardiac muscle

1

0

Small-scale

0.460

High

845988

SCNNG
Amiloride-sensitive sodium channel subunit gamma

1

0

Small-scale

0.460

High

989537

NANGN
NANOG neighbor homeobox

1

0

Small-scale

0.460

High

962746

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

989541

SP20H
Transcription factor SPT20 homolog

1

0

High-throughput

0.458

High

989536

RHOU
Rho-related GTP-binding protein RhoU

1

18

High-throughput

0.457

High

195979

PLXB1
Plexin-B1

1

2

Small-scale

0.439

High

587400

ITIH1
Inter-alpha-trypsin inhibitor heavy chain H1

1

3

Small-scale

0.439

High

173019

RT12
Small ribosomal subunit protein uS12m

1

4

High-throughput

0.437

High

989549

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.437

High

361689

APOC3
Apolipoprotein C-III

1

0

Small-scale

0.288

High

61150

RGSL
Regulator of G-protein signaling protein-like

1

0

Small-scale

0.251

Low

989540

PLD3
5'-3' exonuclease PLD3

1

0

Small-scale

0.251

Low

989553

MINP1
Multiple inositol polyphosphate phosphatase 1

1

0

Small-scale

0.251

Low


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Last updated: 15 Jul 2024