HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0019003 - GDP binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 184
+	Hs
		895026 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49
+	Hs
		895264 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94
+	Hs
		895216 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1C_HUMAN (4-179): 1.37e-69: 211: 30.51
+	Hs
		895028 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		591801 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49
+	Hs
		1273009 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94
+	Zm
		73944 B4FAE1_MAIZE (6-217): 7.18e-86: 254: 39.15		B4FAE1_MAIZE (4-180): 5.71e-75: 225: 35.39
+	Mm
		880395 RAB4A_MOUSE (1-218): 5.01e-88: 260: 97.71		RAB1B_MOUSE (4-179): 1.21e-70: 214: 29.94
+	Hs
		918846 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49
+	Hs
		591800 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		896605 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49
+	Hs
		918944 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94
+	Mm
		919000 RAB1A_MOUSE (3-218): 3.01e-85: 252: 38.43		RAB1B_MOUSE (4-179): 1.21e-70: 214: 29.94
+	Hs
		896681 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94
+	Hs
		913992 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		918847 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		349231 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		350037 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		350016 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		348601 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89