HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: ATRX (P46100)
Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX)
Gene: ATRX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 2492
+	Hs
		595486 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		ARIP4_HUMAN (1298-2492): 0: 681: 27.77
+	Hs
		595436 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		HELLS_HUMAN (1364-2245): 8.17e-147: 482: 19.32
+	Hs
		360457 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		HELLS_HUMAN (1364-2245): 8.17e-147: 482: 19.32
+	Hs
		359939 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		HLTF_HUMAN (1358-2210): 3.39e-129: 436: 16.05
+	Hs
		229272 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		SMCA5_HUMAN (2009-2294): 1.7e-71: 264: 28.28
+	Hs
		359486 K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82		CHD3_HUMAN (33-376): 3.04e-12: 75: 11.08
+	Hs
		531559 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		CHD3_HUMAN (33-376): 3.04e-12: 75: 11.08
+	Hs
		359491 K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82		CHD4_HUMAN (167-398): 6.48e-11: 70.4: 13.60
+	Hs
		595414 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		SMRCD_HUMAN (2010-2209): 4.43e-53: 207: 31.00
+	Hs
		531571 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		CHD4_HUMAN (167-398): 6.48e-11: 70.4: 13.60
+	Hs
		821652 K2C6C_HUMAN (4-407): 3.4e-87: 283: 22.09		CHD3_HUMAN (33-376): 3.04e-12: 75: 11.08
+	Hs
		380468 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		CHD3_HUMAN (33-376): 3.04e-12: 75: 11.08
+	Hs
		821658 K2C6C_HUMAN (4-407): 3.4e-87: 283: 22.09		CHD4_HUMAN (167-398): 6.48e-11: 70.4: 13.60
+	Hs
		380476 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		CHD4_HUMAN (167-398): 6.48e-11: 70.4: 13.60
+	Hs
		595204 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		CHD3_HUMAN (33-376): 3.04e-12: 75: 11.08
+	Hs
		595230 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		CHD4_HUMAN (167-398): 6.48e-11: 70.4: 13.60
+	Hs
		359892 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		CHD3_HUMAN (33-376): 3.04e-12: 75: 11.08
+	Hs
		1018708 KRT84_HUMAN (60-390): 5.25e-59: 208: 20.24		CHD3_HUMAN (33-376): 3.04e-12: 75: 11.08
+	Hs
		1059897 KRT84_HUMAN (60-390): 5.25e-59: 208: 20.24		CHD4_HUMAN (167-398): 6.48e-11: 70.4: 13.60
+	Dr
		71460 B3DKC5_DANRE (6-573): 3.64e-58: 207: 50.76		Q1LYP4_DANRE (21-399): 1.33e-10: 69.7: 12.72