HitPredict

Interactor 1: FILA (P20930)
Filaggrin
Gene: FLG

Interactor 2: GMCL1 (Q96IK5)
Germ cell-less protein-like 1 (Spermatogenesis-associated protein 29)
Gene: GMCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 4061 Hs			1 515
+	Hs
		1125340 FILA2_HUMAN (1661-4000): 4.12e-60: 233: 20.51		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		661391 S10A2_HUMAN (2-98): 9.45e-41: 148: 23.71		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		1291393 S10AG_HUMAN (2-97): 1.67e-33: 128: 19.59		GMCL1_HUMAN (1-515): 0: 543: 100.00
+	Hs
		358608 CO2A1_HUMAN (3607-4048): 5.33e-22: 107: 8.63		KEAP1_HUMAN (31-360): 4.2e-73: 245: 15.00
+	Hs
		990782 COGA1_HUMAN (119-752): 2.15e-17: 92.7: 8.35		KLH12_HUMAN (81-393): 9.98e-75: 248: 16.24
+	Hs
		990784 COGA1_HUMAN (119-752): 2.15e-17: 92.7: 8.35		IPP_HUMAN (83-359): 2.63e-73: 245: 16.35
+	Hs
		132355 CAC1A_HUMAN (499-1001): 6.22e-18: 94.5: 11.82		KLHL1_HUMAN (34-390): 7.34e-70: 239: 15.53
+	Hs
		358512 CO1A1_HUMAN (130-467): 1.31e-10: 70.3: 8.59		KEAP1_HUMAN (31-360): 4.2e-73: 245: 15.00