HitPredict

Interactor 1: RASA1 (P20936)
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)
Gene: RASA1

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1047 Hs			1 474
+	Hs
		596430 RASA1_HUMAN (1-1047): 0: 824: 100.00		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		809479 IQGA1_HUMAN (394-1044): 2.98e-94: 331: 12.78		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		809418 IQGA1_HUMAN (394-1044): 2.98e-94: 331: 12.78		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		1083353 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		RBBP7_HUMAN (14-341): 1.13e-35: 139: 18.94
+	Hs
		986055 PTN11_HUMAN (346-428): 1.05e-19: 96.4: 34.94		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		1299798 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		COR2B_HUMAN (4-218): 5.03e-25: 109: 10.13
+	Hs
		924945 GRB2_HUMAN (181-317): 1.08e-10: 64.3: 30.71		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		809382 IQGA1_HUMAN (394-1044): 2.98e-94: 331: 12.78		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		924828 GRB2_HUMAN (181-317): 1.08e-10: 64.3: 30.71		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		809243 IQGA1_HUMAN (394-1044): 2.98e-94: 331: 12.78		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		924602 GRB2_HUMAN (181-317): 1.08e-10: 64.3: 30.71		RBBP7_HUMAN (14-341): 1.13e-35: 139: 18.94