HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: DCAF6 (Q58WW2)
DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)
Gene: DCAF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37689310, 36688959
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 860
+	Hs
		598163 FLNA_HUMAN (1-2647): 0: 2776: 100.00		DCAF8_HUMAN (2-328): 8.4e-66: 232: 27.60
+	Hs
		598227 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDTC1_HUMAN (13-300): 3.67e-50: 190: 25.72
+	Hs
		598240 FLNA_HUMAN (1-2647): 0: 2776: 100.00		POC1B_HUMAN (585-851): 2.28e-20: 97.3: 12.41
+	Hs
		598345 FLNA_HUMAN (1-2647): 0: 2776: 100.00		NLE1_HUMAN (550-848): 2.26e-18: 91.1: 13.44
+	Hs
		598181 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR82_HUMAN (34-282): 6.27e-17: 84.4: 19.54
+	Hs
		597996 FLNA_HUMAN (1-2647): 0: 2776: 100.00		LIS1_HUMAN (655-815): 5.13e-15: 80: 13.04
+	Hs
		598209 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5B_HUMAN (577-836): 4.46e-14: 76.1: 6.82
+	Hs
		598300 FLNA_HUMAN (1-2647): 0: 2776: 100.00		KTNB1_HUMAN (731-836): 8.83e-13: 74.2: 10.38
+	Hs
		598040 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5_HUMAN (579-832): 1.37e-12: 71.9: 5.81
+	Hs
		598268 FLNA_HUMAN (1-2647): 0: 2776: 100.00		SNR40_HUMAN (704-816): 2.84e-10: 64.9: 21.24
+	Hs
		261236 FLNB_HUMAN (28-2647): 0: 2710: 69.63		WDR5_HUMAN (579-832): 1.37e-12: 71.9: 5.81
+	Mm
		1112495 Q3UGX2_MOUSE (2-460): 6.8e-117: 418: 23.77		WDTC1_MOUSE (13-296): 5.07e-50: 189: 26.06
+	Hs
		903137 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		WDR5_HUMAN (579-832): 1.37e-12: 71.9: 5.81
+	Hs
		725641 ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62		RACK1_HUMAN (44-220): 2.63e-15: 79.8: 21.79
+	Hs
		957556 PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81		SNR40_HUMAN (704-816): 2.84e-10: 64.9: 21.24