Protein: DOCK2
Dedicator of cytokinesis protein 2

Gene: DOCK2
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q92608

Gene Ontology (top 5):
GO:0001766 - membrane raft polarization
GO:0001768 - establishment of T cell polarity
GO:0001771 - immunological synapse formation
GO:0002277 - myeloid dendritic cell activation involved in immune response
GO:0005085 - guanyl-nucleotide exchange factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

925486

RAC1
Ras-related C3 botulinum toxin substrate 1

3

20

Small-scale

0.834

High

545535

RAC2
Ras-related C3 botulinum toxin substrate 2

2

20

Small-scale

0.777

High

1267020

ELMO1
Engulfment and cell motility protein 1

2

20

Small-scale

0.767

High

642125

KRA59
Keratin-associated protein 5-9

3

16

High-throughput

0.675

High

889608

KR108
Keratin-associated protein 10-8

3

14

High-throughput

0.675

High

904061

HNRPK
Heterogeneous nuclear ribonucleoprotein K

3

1

High-throughput

0.675

High

1127090

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

4

High-throughput

0.675

High

1149263

K1C40
Keratin, type I cytoskeletal 40

3

3

High-throughput

0.675

High

1267936

MDFI
MyoD family inhibitor

3

0

High-throughput

0.646

High

1189380

NT2NA
Notch homolog 2 N-terminal-like protein A

2

4

High-throughput

0.633

High

548738

VAV
Proto-oncogene vav

1

6

Small-scale

0.618

High

802881

CRKL
Crk-like protein

1

17

Small-scale

0.618

High

882467

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

6

High-throughput

0.618

High

1267934

ELMO2
Engulfment and cell motility protein 2

1

20

High-throughput

0.618

High

1139247

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

3

3

High-throughput

0.616

High

280674

KRT34
Keratin, type I cuticular Ha4

2

3

High-throughput

0.606

High

611301

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

2

High-throughput

0.606

High

889351

KR107
Keratin-associated protein 10-7

2

14

High-throughput

0.606

High

991635

KRA11
Keratin-associated protein 1-1

2

14

High-throughput

0.606

High

1071310

K1H1
Keratin, type I cuticular Ha1

2

3

High-throughput

0.606

High

1154161

KRA57
Keratin-associated protein 5-7

2

15

High-throughput

0.606

High

1154498

TEN4
Teneurin-4

2

3

High-throughput

0.606

High

1216363

KRA13
Keratin-associated protein 1-3

2

11

High-throughput

0.606

High

1267937

CAR10
Caspase recruitment domain-containing protein 10

2

2

High-throughput

0.606

High

1267940

KRA93
Keratin-associated protein 9-3

2

11

High-throughput

0.606

High

1267943

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.606

High

1267944

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.606

High

67261

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

888604

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.580

High

1267932

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.580

High

1267938

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.580

High

734716

TRI23
E3 ubiquitin-protein ligase TRIM23

1

2

High-throughput

0.573

High

889850

KR109
Keratin-associated protein 10-9

1

15

High-throughput

0.573

High

1025487

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

2

High-throughput

0.573

High

1267939

KRA94
Keratin-associated protein 9-4

1

11

High-throughput

0.573

High

1267941

KRA92
Keratin-associated protein 9-2

1

11

High-throughput

0.573

High

1267942

KRA42
Keratin-associated protein 4-2

1

11

High-throughput

0.573

High

62378

GG6L9
Golgin subfamily A member 6-like protein 9

2

6

High-throughput

0.553

High

267531

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

2

3

High-throughput

0.553

High

829956

HXA1
Homeobox protein Hox-A1

2

3

High-throughput

0.553

High

1267945

PKHF2
Pleckstrin homology domain-containing family F member 2

2

2

High-throughput

0.553

High

170114

PLS1
Phospholipid scramblase 1

1

0

High-throughput

0.549

High

310204

CCDB1
Cyclin-D1-binding protein 1

1

0

High-throughput

0.549

High

167759

FYB1
FYN-binding protein 1

1

0

Small-scale

0.546

High

484676

NT2NC
Notch homolog 2 N-terminal-like protein C

1

5

High-throughput

0.515

High

497370

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.515

High

152316

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

2

Small-scale

0.501

High

1026933

PAK2
Serine/threonine-protein kinase PAK 2

1

2

Small-scale

0.501

High

1267935

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

1

0

High-throughput

0.493

High

1039728

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.489

High

888752

KR101
Keratin-associated protein 10-1

1

15

High-throughput

0.481

High

888949

KR103
Keratin-associated protein 10-3

1

15

High-throughput

0.481

High

210171

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

569917

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

657397

ABCD3
ATP-binding cassette sub-family D member 3

1

1

High-throughput

0.479

High

832613

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

1146682

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

590

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.460

High

329862

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

596586

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

Small-scale

0.458

High

673506

MPIP2
M-phase inducer phosphatase 2

1

0

High-throughput

0.458

High

869697

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.458

High

1267933

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

991830

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

3

Small-scale

0.408

High

831533

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.373

High

1267946

Q9P1N4
PRO1359

1

0

High-throughput

0.268

Low

1146137

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024