HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2647 Hs			1 1121
+	Hs
		598171 FLNA_HUMAN (1-2647): 0: 2776: 100.00		NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13
+	Hs
		598221 FLNA_HUMAN (1-2647): 0: 2776: 100.00		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		598332 FLNA_HUMAN (1-2647): 0: 2776: 100.00		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		125152 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		598320 FLNA_HUMAN (1-2647): 0: 2776: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		261331 FLNB_HUMAN (28-2647): 0: 2710: 69.63		SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18
+	Hs
		598120 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Hs
		261327 FLNB_HUMAN (28-2647): 0: 2710: 69.63		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		261264 FLNB_HUMAN (28-2647): 0: 2710: 69.63		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Hs
		1052944 FLNC_HUMAN (32-2647): 0: 1432: 35.96		SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18
+	Hs
		1052940 FLNC_HUMAN (32-2647): 0: 1432: 35.96		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		521561 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		963422 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		963426 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Mm
		1143715 SPTB2_MOUSE (22-460): 2.2e-118: 423: 24.62		CNKR2_MOUSE (119-516): 8.05e-46: 181: 17.87
+	Hs
		521574 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		521619 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		963417 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		725697 ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		521613 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84