HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: FLIP1 (Q7Z7B0)
Filamin-A-interacting protein 1 (FILIP)
Gene: FILIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	12055638
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2647 Hs			1 1213
+	Hs
		597987 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MYH11_HUMAN (87-963): 3.32e-41: 168: 13.39
+	Hs
		148392 FLNA_HUMAN (1-2647): 0: 2776: 100.00		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		597985 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MYH9_HUMAN (367-991): 5.2e-25: 115: 11.61
+	Hs
		598338 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MYO5C_HUMAN (154-658): 8.87e-12: 72: 22.12
+	Hs
		598207 FLNA_HUMAN (1-2647): 0: 2776: 100.00		LUZP1_HUMAN (72-497): 3.65e-10: 66.6: 18.01
+	Hs
		148205 FLNB_HUMAN (28-2647): 0: 2710: 69.63		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		598255 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38
+	Hs
		261212 FLNB_HUMAN (28-2647): 0: 2710: 69.63		MYH9_HUMAN (367-991): 5.2e-25: 115: 11.61
+	Hs
		261303 FLNB_HUMAN (28-2647): 0: 2710: 69.63		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38
+	Hs
		148807 FLNC_HUMAN (32-2647): 0: 1432: 35.96		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		148690 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		148330 SPTB1_HUMAN (2-460): 2.89e-117: 419: 23.57		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		148463 ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		724781 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		MYH9_HUMAN (367-991): 5.2e-25: 115: 11.61
+	Hs
		148339 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		148722 ACTN3_HUMAN (30-460): 2.85e-118: 401: 25.28		CTRO_HUMAN (20-666): 3.2e-30: 132: 11.57
+	Hs
		521484 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		MYH9_HUMAN (367-991): 5.2e-25: 115: 11.61
+	Hs
		963335 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		ITSN1_HUMAN (38-410): 9e-16: 85.3: 10.11
+	Hs
		963431 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		MYO5C_HUMAN (154-658): 8.87e-12: 72: 22.12
+	Hs
		963381 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38