HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: CHM4C (Q96CF2)
Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c) (SNF7 homolog associated with Alix 3) (SNF7-3) (hSnf7-3) (Vacuolar protein sorting-associated protein 32-3) (Vps32-3) (hVps32-3)
Gene: CHMP4C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0042803 - protein homodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 233
+	Hs
		598318 FLNA_HUMAN (1-2647): 0: 2776: 100.00		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		261308 FLNB_HUMAN (28-2647): 0: 2710: 69.63		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		261326 FLNB_HUMAN (28-2647): 0: 2710: 69.63		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		1052920 FLNC_HUMAN (32-2647): 0: 1432: 35.96		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		1052937 FLNC_HUMAN (32-2647): 0: 1432: 35.96		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		963386 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		506831 SPTB1_HUMAN (2-460): 2.89e-117: 419: 23.57		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		725686 ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		521595 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		993280 ACTN3_HUMAN (30-460): 2.85e-118: 401: 25.28		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		963414 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		506841 SPTB1_HUMAN (2-460): 2.89e-117: 419: 23.57		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		211642 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		725696 ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		521612 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		993293 ACTN3_HUMAN (30-460): 2.85e-118: 401: 25.28		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		211663 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78