Interactor 1: MK03 (P21708)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: Mapk3

Interactor 2: MK01 (P63086)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 20181831, 19935650
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0001784 - phosphotyrosine residue binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity
and 61 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 380
Rn

1 358
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ Dm
+ At
+ Hs
+ Zm
+ At
+ At
+ Kl
+ At
+ At
+ At
+ At
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+ Hs
+ Hs

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Last updated: 15 Jul 2024