Protein: AMPL
Cytosol aminopeptidase (EC 3.4.11.1) (Cysteinylglycine-S-conjugate dipeptidase) (EC 3.4.13.23) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (Peptidase S) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase)

Gene: AMPL, LAP3
Organism: Homo sapiens
Interactions: 58
UniProt ID: P28838

Gene Ontology (top 5):
GO:0004177 - aminopeptidase activity
GO:0004180 - carboxypeptidase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

226601

PRKN
E3 ubiquitin-protein ligase parkin

3

1

High-throughput

0.640

High

607787

USF1
Upstream stimulatory factor 1

2

2

High-throughput

0.606

High

660949

CBX5
Chromobox protein homolog 5

2

1

High-throughput

0.606

High

660958

CBX3
Chromobox protein homolog 3

2

1

High-throughput

0.606

High

660964

ZYX
Zyxin

2

1

High-throughput

0.606

High

660948

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.580

High

660971

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.580

High

660985

MARE3
Microtubule-associated protein RP/EB family member 3

2

0

High-throughput

0.580

High

660951

DNLI4
DNA ligase 4

1

1

High-throughput

0.552

High

660956

KPCE
Protein kinase C epsilon type

2

0

High-throughput

0.547

High

660952

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.518

High

610808

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.513

High

660953

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.513

High

660962

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.486

High

174642

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

394166

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

346007

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

641627

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

High-throughput

0.479

High

660966

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

660967

ARMC8
Armadillo repeat-containing protein 8

1

1

High-throughput

0.479

High

660974

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

660986

RPGF2
Rap guanine nucleotide exchange factor 2

1

1

High-throughput

0.479

High

214107

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

298189

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

397801

ISG15
Ubiquitin-like protein ISG15

1

0

High-throughput

0.458

High

503498

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

660954

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

660955

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

660959

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

660960

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

660963

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

660965

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.458

High

660972

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

660975

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.458

High

660979

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.458

High

660980

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

0

High-throughput

0.458

High

660982

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

660983

TES
Testin

1

0

High-throughput

0.458

High

496373

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

517073

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

660957

GCNT1
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

1

0

Small-scale

0.438

High

660976

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.438

High

660984

TPC2L
Trafficking protein particle complex subunit 2-like protein

1

0

Small-scale

0.438

High

382317

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.426

High

401474

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

660969

BANP
Protein BANP

2

0

High-throughput

0.316

High

660973

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

0

High-throughput

0.316

High

217543

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

660961

RBM39
RNA-binding protein 39

1

0

High-throughput

0.279

Low

660968

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.279

Low

660977

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

660981

ZCC17
Zinc finger CCHC domain-containing protein 17

1

0

High-throughput

0.279

Low

660987

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.279

Low

384326

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

660947

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

660950

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

660970

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

660978

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024