HitPredict

Interactor 1: EPHA1 (P21709)
Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)
Gene: EPHA1

Interactor 2: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, FERM_M~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Y_phosphatase, PDZ~SAM_1, SAM_1~Y_phosphatase
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 2485
+	Hs
		1020163 EPHA7_HUMAN (2-975): 0: 1117: 43.22		PTN13_HUMAN (1-2485): 0: 1895: 100.00
+	Hs
		872431 EPHA5_HUMAN (3-975): 0: 1117: 41.91		PTN13_HUMAN (1-2485): 0: 1895: 100.00
+	Hs
		665589 EPHB2_HUMAN (27-975): 0: 1112: 41.01		PTN13_HUMAN (1-2485): 0: 1895: 100.00
+	Hs
		872638 EPHA4_HUMAN (5-975): 0: 1108: 43.50		PTN13_HUMAN (1-2485): 0: 1895: 100.00
+	Hs
		665393 EPHA3_HUMAN (22-975): 0: 1097: 43.01		PTN13_HUMAN (1-2485): 0: 1895: 100.00
+	Hs
		665228 EPHA2_HUMAN (24-976): 0: 1056: 49.90		PTN13_HUMAN (1-2485): 0: 1895: 100.00
+	Hs
		872429 EPHA5_HUMAN (3-975): 0: 1117: 41.91		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		985961 EPHA7_HUMAN (2-975): 0: 1117: 43.22		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		665554 EPHB2_HUMAN (27-975): 0: 1112: 41.01		MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65
+	Hs
		719689 EPHA5_HUMAN (3-975): 0: 1117: 41.91		RADI_HUMAN (574-969): 6.68e-116: 383: 26.94
+	Hs
		665555 EPHB2_HUMAN (27-975): 0: 1112: 41.01		RADI_HUMAN (574-969): 6.68e-116: 383: 26.94
+	Hs
		872635 EPHA4_HUMAN (5-975): 0: 1108: 43.50		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		600558 EPHA1_HUMAN (1-976): 0: 1103: 100.00		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		665158 EPHA2_HUMAN (24-976): 0: 1056: 49.90		MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65
+	Hs
		665220 EPHA2_HUMAN (24-976): 0: 1056: 49.90		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		616944 EPHA8_HUMAN (27-975): 0: 1033: 40.90		PTPRD_HUMAN (2189-2468): 1.65e-92: 337: 30.72
+	Hs
		573629 EPHA5_HUMAN (3-975): 0: 1117: 41.91		PTN1_HUMAN (2229-2465): 2.56e-45: 172: 37.40
+	Hs
		573583 EPHA8_HUMAN (27-975): 0: 1033: 40.90		PTN1_HUMAN (2229-2465): 2.56e-45: 172: 37.40
+	Hs
		872669 EPHA4_HUMAN (5-975): 0: 1108: 43.50		MAGI2_HUMAN (873-1270): 1.19e-11: 72.9: 16.50
+	Hs
		204618 UFO_HUMAN (274-964): 2.03e-146: 459: 23.29		E41L2_HUMAN (367-1065): 2.11e-113: 389: 17.33